Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans
NCT ID: NCT02781519
Last Updated: 2025-06-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
PHASE1
100 participants
INTERVENTIONAL
2015-06-30
2026-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
QUADRUPLE
Study Groups
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THC
Active THC (0.015mg/kg) administered intravenously over 10 minutes.
THC
Active THC (0.015mg/kg) administered over 10 minutes
Placebo
Control: small amount of alcohol intravenously (quarter teaspoon), with no THC over 10 minutes.
Placebo
Control: small amount of alcohol (quarter teaspoon), with no THC over 10 minutes
Interventions
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THC
Active THC (0.015mg/kg) administered over 10 minutes
Placebo
Control: small amount of alcohol (quarter teaspoon), with no THC over 10 minutes
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* good physical and mental health
Exclusion Criteria
* major current or recent stressors
* taking estrogen supplements or oral contraceptive pills (for women)
18 Years
55 Years
ALL
Yes
Sponsors
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Yale University
OTHER
Responsible Party
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Mohini Ranganathan
Assistant Professor of Psychiatry
Locations
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Biological Studies Unit at the VA Connecticut Healthcare System, Yale School of Medicine
West Haven, Connecticut, United States
Countries
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Central Contacts
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Facility Contacts
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References
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Mohammad Aghaei A, Urban Spillane L, Pittman B, Flynn LT, De Aquino JP, Bassir Nia A, Ranganathan M. Sex differences in the acute effects of oral THC: a randomized, placebo-controlled, crossover human laboratory study. Psychopharmacology (Berl). 2024 Oct;241(10):2145-2155. doi: 10.1007/s00213-024-06625-6. Epub 2024 Jun 4.
Other Identifiers
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1505015940
Identifier Type: -
Identifier Source: org_study_id
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