Influence of Central Obesity on the Esophageal Epithelial Barrier
NCT ID: NCT02776982
Last Updated: 2022-02-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
38 participants
INTERVENTIONAL
2016-11-30
2019-05-16
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Research procedures
Participants enrolled in study will have confocal endomicroscopy, research biopsies, mucosal impedance, and Bravo ambulatory pH capsule performed at the time of clinically indicated endoscopy.
Confocal endomicroscopy
Confocal endomicroscopy will be performed during clinically indicated endoscopy.
Mucosal impedance
Mucosal impedance will be performed at the time of clinically indicated endoscopy.
Research biopsies
Research biopsies will be obtained during clinically indicated endoscopy.
Bravo ambulatory pH monitor
Bravo ambulatory pH capsule will be placed during clinically indicated endoscopy.
Interventions
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Confocal endomicroscopy
Confocal endomicroscopy will be performed during clinically indicated endoscopy.
Mucosal impedance
Mucosal impedance will be performed at the time of clinically indicated endoscopy.
Research biopsies
Research biopsies will be obtained during clinically indicated endoscopy.
Bravo ambulatory pH monitor
Bravo ambulatory pH capsule will be placed during clinically indicated endoscopy.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
2. Oral anticoagulation precluding endoscopic biopsies
3. Patients with known hypersensitivity to fluorescein sodium.
18 Years
85 Years
ALL
Yes
Sponsors
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Mayo Clinic
OTHER
Responsible Party
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Prasad G. Iyer
MD
Principal Investigators
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Prasad G Iyer, MD
Role: PRINCIPAL_INVESTIGATOR
Mayo Clinic
Locations
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Mayo Clinic
Rochester, Minnesota, United States
Countries
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References
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Gibbens YY, Lansing R, Johnson ML, Blevins CH, Katzka DA, Iyer PG. Effects of Central Obesity on Esophageal Epithelial Barrier Function. Am J Gastroenterol. 2021 Jul 1;116(7):1537-1541. doi: 10.14309/ajg.0000000000001196.
Related Links
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Mayo Clinic Clinical Trials
Other Identifiers
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16-001069
Identifier Type: -
Identifier Source: org_study_id
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