Incidence of Caries in Smoking and Smokeless Tobacco

NCT ID: NCT02767050

Last Updated: 2016-05-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

613 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-12-31

Study Completion Date

2016-02-29

Brief Summary

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The following observational study evaluates incidence of caries in smoking and smokeless tobacco based on habit history by clinical examination and DMFT index.

Detailed Description

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Dental caries is an irreversible microbial disease of the calcified tissues of the teeth, characterized by demineralization of the inorganic portion and destruction of the organic substance of the tooth, which often leads to cavitation. It is a complex and dynamic process where a multitude of factors influence and initiate the progression of disease. There are practically no geographic areas in the world whose inhabitants do not exhibit some evidence of dental caries. It affects persons of both genders in all races, all socioeconomic strata and every age group. Likewise, there is strong evidence that tobacco use has numerous negative effects on oral health, for example staining of teeth, dental restoration, development of oral diseases. A biologically reasonable explanation for an association between chewing tobacco use and dental caries may be the presence of higher levels of fermentable sugars in chewing tobacco products which can stimulate the growth of carcinogenic bacteria. The decreased buffering effect possible lower pH of smokers saliva and higher number of lactobacilli and streptococcus mutans group may indicate an increased susceptibility to caries in smokers. On the other hand, there are researches which conclude that presence of extrinsic tobacco stains appear to provide a protective effect from caries.

Conditions

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DENTAL CARIES

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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GROUP 1: CONTROL GROUPS

Patients with no habit history of tobacco are included in group 1.

No interventions assigned to this group

GROUP 2: SMOKING TOBACCO

Patients with a history of tobacco consumption in the form of smoking.

No interventions assigned to this group

GROUP 3: SMOKELESS TOBACCO

Patients with a history of tobacco consumption in the form of chewing.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients who are willing for the study.
* A positive history of dental caries in smokers and smokeless tobacco.
* Patients with caries not under any treatment of the same.

Exclusion Criteria

* Unwilling patients who do not want to be a part of the study.
* Patient with fluorosis.
Minimum Eligible Age

15 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre

OTHER

Sponsor Role lead

Responsible Party

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Dr.Alekhya

Resident

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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NALLAN CHAITANYA, MDS

Role: PRINCIPAL_INVESTIGATOR

Panineeya Mahavidhyalaya Institute of Dental Sciences and Research Centre

Locations

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Panineeya Institute of Dental Sciences

Hyderabad, Telangana, India

Site Status

Countries

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India

References

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Vellappally S, Jacob V, Smejkalova J, Shriharsha P, Kumar V, Fiala Z. Tobacco habits and oral health status in selected Indian population. Cent Eur J Public Health. 2008 Jun;16(2):77-84. doi: 10.21101/cejph.a3448.

Reference Type RESULT
PMID: 18661810 (View on PubMed)

Vellappally S, Fiala Z, Smejkalova J, Jacob V, Shriharsha P. Influence of tobacco use in dental caries development. Cent Eur J Public Health. 2007 Sep;15(3):116-21. doi: 10.21101/cejph.a3431.

Reference Type RESULT
PMID: 17958204 (View on PubMed)

Rooban T, Vidya K, Joshua E, Rao A, Ranganathan S, Rao UK, Ranganathan K. Tooth decay in alcohol and tobacco abusers. J Oral Maxillofac Pathol. 2011 Jan;15(1):14-21. doi: 10.4103/0973-029X.80032.

Reference Type RESULT
PMID: 21731272 (View on PubMed)

Other Identifiers

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PMVIDS&RC/IEC/OMR/PR/0046-15

Identifier Type: -

Identifier Source: org_study_id

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