The Effect of Perioperative Lidocaine Intravenous Infusion on Postoperative Recovery After Spine Surgery.
NCT ID: NCT02762656
Last Updated: 2016-05-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
60 participants
INTERVENTIONAL
2016-06-30
2017-08-31
Brief Summary
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Detailed Description
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Sixty patients scheduled for a spine surgery will be randomly assigned to two groups. Lidocaine group will receive an intravenous bolus injection of lidocaine 1.5 mg/kg before intubation, followed by 2 mg/kg/h continuous infusion during the operation. Placebo group will receive the same dosage of saline at the same time. Analgesic requirement will be monitored using patient-controlled Analgesia (PCA protocol: demand dose is 2 mg of morphine, lockout 5 min, maximum dose 15 mg per hour). Forty-eight hours after surgery, we will check the morphine consumption in two groups. Quality of recovery after surgery will be assessed using Q0R15 questionnaire.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Lidocaine
Patients will receive Lidocaine drip during spine surgery
Lidocaine
Lidocaine drip during surgery
Placebo
Patients will receive placebo during spine surgery
Lidocaine
Lidocaine drip during surgery
Interventions
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Lidocaine
Lidocaine drip during surgery
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* hepatic disease
* dementia or cognitive decline
18 Years
60 Years
ALL
Yes
Sponsors
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Sheba Medical Center
OTHER_GOV
Responsible Party
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Locations
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Sheba Medical Center
Ramat Gan, , Israel
Countries
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Central Contacts
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Related Links
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Intraoperative systemic infusion of lidocaine reduces postoperative pain after lumbar surgery: a double-blinded, randomized, placebo-controlled clinical trial.
Intravenous lidocaine for effective pain relief after a laparoscopic colectomy: a prospective, randomized, double-blind, placebo-controlled study.
Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery.
Other Identifiers
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SHEBA-16-2972-VS-CTIL
Identifier Type: -
Identifier Source: org_study_id
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