Impact of Peripheral Nerve Blockade on Outcomes After Total Knee Replacement

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

178214 participants

Study Classification

OBSERVATIONAL

Study Start Date

2002-04-30

Study Completion Date

2014-03-31

Brief Summary

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Pain is common after knee replacement surgery and can impact a variety of patient outcomes. Peripheral nerve blocks provide improved pain control and may improve function. However, their impact on other outcomes is poorly described. Therefore, this comparative effectiveness study will estimate the independent association between nerve blocks and health outcomes after knee replacement surgery.

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Detailed Description

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This retrospective, population-based cohort study will evaluate the comparative effectiveness of peripheral nerve blocks on patient and health system outcomes after elective total knee replacement surgery.

The investigators will develop a non-parsimonious propensity score to control for potential indication bias and confounding in this observational study. Using the propensity score the investigators will match patients who receive a peripheral nerve block to a patient who did not to estimate the independent association of peripheral nerve blocks with our study outcomes.

Conditions

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Pain Osteoarthritis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Peripheral nerve block

Intervention arm. Participants who receive a peripheral nerve block identified through submission of an appropriate physician billing code

Peripheral nerve block

Intervention Type OTHER

A physician billing code for deposition of a local anesthetic solution around an anatomically defined nerve or nerve plexus

No peripheral nerve block

Control arm. Participants who do not receive a peripheral nerve block identified through lack of a submission of an appropriate physician billing code

No interventions assigned to this group