Comparing Cardiovascular Effects of 1:100,000 and 1:200,000 Epinephrine Solutions

NCT ID: NCT02735018

Last Updated: 2016-04-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-12-31

Study Completion Date

2015-03-31

Brief Summary

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The study aim to evaluate systemic response of patients when 2 different concentrations of Epinephrine are injected during inferior alveolar nerve block for wisdom teeth extraction.

Detailed Description

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Conditions

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Cardiovascular Response to Epinephrine

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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Epinephrine 1:100,000

Inferior alveolar nerve block with Epinephrine 1:100.000

Group Type EXPERIMENTAL

Epinephrine 1:100,000

Intervention Type DRUG

Inferior alveolar nerve block with Epinephrine 1:100.000

Epinephrine 1:200,000

Inferior alveolar nerve block with Epinephrine 1:200.000

Group Type EXPERIMENTAL

Epinephrine 1:200,000

Intervention Type DRUG

Inferior alveolar nerve block with Epinephrine 1:200.000

Interventions

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Epinephrine 1:100,000

Inferior alveolar nerve block with Epinephrine 1:100.000

Intervention Type DRUG

Epinephrine 1:200,000

Inferior alveolar nerve block with Epinephrine 1:200.000

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Class I patients according to the American Society of Anesthesiology (ASA),
* Indication for third molars extraction,
* Similar degree of complexity, according to the classification of Pell and Gregory.

Exclusion Criteria

* Patients with systemic conditions,
* Patients with known allergy to any component of the anesthetic solution.
Minimum Eligible Age

13 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Rio de Janeiro State University

OTHER

Sponsor Role lead

Responsible Party

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Fabio Ritto

DDS, MD, MS, PhD, Program Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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496.117

Identifier Type: -

Identifier Source: org_study_id

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