Effectiveness of Isometric vs. Eccentric Exercise in Chronic Achilles Tendinopathy
NCT ID: NCT02732782
Last Updated: 2021-02-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
45 participants
INTERVENTIONAL
2016-08-31
2020-10-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Isometric exercise
Isometric exercise (90% maximum voluntary contraction (MVC), 12 weeks, 4 times a week, 5 sets of 4 repetitions a 3 seconds)
Isometric exercise
Eccentric exercise
Eccentric training ("Alfredson" approach, 12 weeks, 2 sets per day with extended and two sets per day with bended knee, 15 repetitions per set)
Eccentric exercise
Control
Control, no intervention
No interventions assigned to this group
Interventions
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Isometric exercise
Eccentric exercise
Eligibility Criteria
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Inclusion Criteria
* age 18-60
* male
* VISA-A Score of at least 80
Exclusion Criteria
* any systemic or inflammatory diseases (i. e. Diabetes, Arthritis)
* surgery on lower extremities in the past
* corticoid injections in the last 12 months
20 Years
50 Years
MALE
No
Sponsors
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Charite University, Berlin, Germany
OTHER
Humboldt-Universität zu Berlin
OTHER
Responsible Party
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Goran Radovanovic
Principal Investigator
Principal Investigators
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Kirsten Legerlotz, PhD, Prof
Role: STUDY_DIRECTOR
Humboldt Universität zu Berlin, Department of Movement Sciences
Locations
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Humboldt Universität zu Berlin, Institut für Bewegungswissenschaften, Department Movement Sciences
Berlin, , Germany
Countries
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References
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Legerlotz K, Jones ER, Screen HR, Riley GP. Increased expression of IL-6 family members in tendon pathology. Rheumatology (Oxford). 2012 Jul;51(7):1161-5. doi: 10.1093/rheumatology/kes002. Epub 2012 Feb 15.
Mersmann F, Bohm S, Schroll A, Boeth H, Duda GN, Arampatzis A. Muscle and tendon adaptation in adolescent athletes: A longitudinal study. Scand J Med Sci Sports. 2017 Jan;27(1):75-82. doi: 10.1111/sms.12631. Epub 2015 Dec 8.
Arampatzis A, Karamanidis K, Mademli L, Albracht K. Plasticity of the human tendon to short- and long-term mechanical loading. Exerc Sport Sci Rev. 2009 Apr;37(2):66-72. doi: 10.1097/JES.0b013e31819c2e1d.
Radovanovic G, Bohm S, Peper KK, Arampatzis A, Legerlotz K. Evidence-Based High-Loading Tendon Exercise for 12 Weeks Leads to Increased Tendon Stiffness and Cross-Sectional Area in Achilles Tendinopathy: A Controlled Clinical Trial. Sports Med Open. 2022 Dec 20;8(1):149. doi: 10.1186/s40798-022-00545-5.
Other Identifiers
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AZ: ZMV14-070102/16-17
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
PR020151100167
Identifier Type: -
Identifier Source: org_study_id
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