Study of OZURDEX® in the Treatment of Diabetic Macular Oedema (DME) in Australia - The AUSSIEDEX Study

NCT ID: NCT02731911

Last Updated: 2019-01-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

202 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-04-29

Study Completion Date

2018-10-22

Brief Summary

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This prospective study will assess Ozurdex in the treatment of Diabetic Macular Oedema in clinical practice.

Detailed Description

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Conditions

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Diabetic Macular Oedema

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Ozurdex® (dexamethasone intravitreal implant)

Patients who received Ozurdex® in the treatment of Diabetic Macular Oedema per local standard of care in clinical practice.

dexamethasone intravitreal implant

Intervention Type DRUG

Ozurdex® treatment for diabetic macular oedema as per standard of care in clinical practice.

Interventions

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dexamethasone intravitreal implant

Ozurdex® treatment for diabetic macular oedema as per standard of care in clinical practice.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Pseudophakic or phakic and scheduled for a cataract operation
* Macular oedema due to DME

Exclusion Criteria

* Previous Ozurdex® treatment
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Allergan

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Dr. George Labib

Role: STUDY_DIRECTOR

Allergan

Locations

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Retina and Macula Specialists,Hurstville

Hurtsville, New South Wales, Australia

Site Status

Retina Associates

Liverpool, New South Wales, Australia

Site Status

Retina and Macula Specialists, Miranda

Miranda, New South Wales, Australia

Site Status

Eye Doctors Mona Vale

Mona Vale, New South Wales, Australia

Site Status

Marsden Eye Clinic

Parramatta, New South Wales, Australia

Site Status

Retina & Vitreous Centre Strathfield

Strathfield, New South Wales, Australia

Site Status

Strathfield Retina

Strathfield, New South Wales, Australia

Site Status

Retina & Vitreous Centre City

Sydney, New South Wales, Australia

Site Status

Sydney Eye and Retina Clinic

Sydney, New South Wales, Australia

Site Status

Sydney Eye Hospital/Macular Diseases Centre

Sydney, New South Wales, Australia

Site Status

Sydney West Retina

Westmead, New South Wales, Australia

Site Status

Terrace Eye Centre

Brisbane, Queensland, Australia

Site Status

Caboolture Eye Surgery

Caboolture, Queensland, Australia

Site Status

Peninsula Eye Hospital

Redcliffe, Queensland, Australia

Site Status

The Qld Eye Institute

South Brisbane, Queensland, Australia

Site Status

Adelaide Eye & Retina Centre

Adelaide, South Australia, Australia

Site Status

Department of Opthalmology, Royal Adelaide Hospital

Adelaide, South Australia, Australia

Site Status

Hobart Eye Surgeons

Hobart, Tasmania, Australia

Site Status

Tasmanian Eye Institute

Launceston, Tasmania, Australia

Site Status

Essendon Retina

Essendon, Victoria, Australia

Site Status

Victoria Parade Eye Consultants

Fitzroy, Victoria, Australia

Site Status

Vision Eye Institute

Footscry, Victoria, Australia

Site Status

Lions Eye Institute

Nedlands, Western Australia, Australia

Site Status

Countries

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Australia

References

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Mitchell P, Arnold J, Fraser-Bell S, Kang HK, Chang AA, Tainton J, Simonyi S. Dexamethasone intravitreal implant in diabetic macular oedema refractory to anti-vascular endothelial growth factors: the AUSSIEDEX study. BMJ Open Ophthalmol. 2023 Aug;8(1):e001224. doi: 10.1136/bmjophth-2022-001224.

Reference Type DERIVED
PMID: 37541745 (View on PubMed)

Fraser-Bell S, Kang HK, Mitchell P, Arnold JJ, Tainton J, Simonyi S. Dexamethasone intravitreal implant in treatment-naive diabetic macular oedema: findings from the prospective, multicentre, AUSSIEDEX study. Br J Ophthalmol. 2023 Jan;107(1):72-78. doi: 10.1136/bjophthalmol-2021-319070. Epub 2021 Aug 25.

Reference Type DERIVED
PMID: 34433549 (View on PubMed)

Other Identifiers

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CMO-AP-EYE-0438

Identifier Type: -

Identifier Source: org_study_id

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