Standard Treatments of Very-early Stage Hepatocellular Carcinoma

NCT ID: NCT02728193

Last Updated: 2016-04-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-12-31

Study Completion Date

2015-12-31

Brief Summary

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The aim of our study was to elucidate the difference in the rates of complication, hospitalization days, medical expenses, MRI showed that the degree of tumor necrosis, and overall survival rates of the therapies between PEI, MVA and RFA, and make the standard for minimally invasive treatment of very early stage HCC.

Detailed Description

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Conditions

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Hepatocellular Carcinoma Very-early Stage

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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RFA

Radiofrequency ablation

Group Type EXPERIMENTAL

RFA

Intervention Type PROCEDURE

MWV

Microwave ablation

Group Type EXPERIMENTAL

MWV

Intervention Type PROCEDURE

PEI

Percutaneous ethanol injection

Group Type EXPERIMENTAL

PEI

Intervention Type PROCEDURE

Percutaneous ethanol injection

Interventions

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RFA

Intervention Type PROCEDURE

MWV

Intervention Type PROCEDURE

PEI

Percutaneous ethanol injection

Intervention Type PROCEDURE

Other Intervention Names

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Microwave ablation

Eligibility Criteria

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Inclusion Criteria

1. Preoperative clinical, imaging and tumor markers were diagnosed as hepatocellular carcinoma
2. Tumor diameter\<2cm
3. Child-Pugh class A liver function
4. Without major organ dysfunction
5. male or female patients \> 18 years and \<=70 years of age
6. Voluntary participation in this clinical trial

Exclusion Criteria

1. Other anticancer treatment before therapy
2. Patients with apparent major organs (i.e. cardiac, pulmonary, cerebral and renal) dysfunction, which may affect the treatment of liver cancer
3. Patients with other diseases that may affect the treatment of this treatment
4. History of other malignant tumors
5. Patients who are participating in other clinical trials
6. Pregnant, lactating women
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Eastern Hepatobiliary Surgery Hospital

OTHER

Sponsor Role lead

Responsible Party

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ShenFeng

vice president of the Eastern Hepatobiliary Surgery Hospotal

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Eastern hepatobilliary surgery hospital

Shanghai, Shanghai Municipality, China

Site Status

Countries

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China

Other Identifiers

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2012ZX10002016003001

Identifier Type: -

Identifier Source: org_study_id

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