Effect of Frequent Interruptions of Prolonged Sitting on Self-perceived Levels of Energy, Mood, Food Cravings and Cognitive Function

NCT ID: NCT02717377

Last Updated: 2016-03-23

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2013-11-30
• Study Completion Date: 2014-05-31

Brief Summary

This study is designed to test the effects of six 5 minute microbursts of physical activity spread across the day as compared to either a sedentary control condition or a single 30 minute bout of moderate intensity physical activity on cognitive function, self-reported energy levels, aspects of eating behavior and measures of metabolic health. The primary hypotheses are:

1. Hourly 5 minute bouts of moderate intensity exercise during the day will increase afternoon cognitive function as compared to a no exercise condition.

2. Hourly 5 minute bouts of moderate intensity exercise during the day will increase afternoon cognitive function more than a single 30 minute AM bout.

Secondary exploratory hypotheses include

1. Hourly 5 minute bouts of moderate intensity exercise during the day will increase self-reported energy levels, reduce orexigenic appetitive measures and improve measures of metabolic health as compared to a no exercise condition.

2. Hourly 5 minute bouts of moderate intensity exercise during the day will increase self-reported energy levels, reduce orexigenic appetitive measures and improve measures of metabolic health more than a single 30 minute AM bout.

Conditions

Mood; Energy; Food Cravings; Cognitive Function

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: PREVENTION
• Blinding Strategy: SINGLE

Study Groups

Uninterrupted sitting

Subjects remained seated all day except to rise from the chair to void.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Sitting + one bout of activity

Subjects remained seated all day, except to rise from the chair to void, and to perform one bout of 30-minutes moderate-intensity walking. Physical activity was performed at 0800, after measures of vitals and basal questionnaire assessments, but before breakfast.

Group Type: ACTIVE_COMPARATOR

physical activity

Intervention Type: BEHAVIORAL

Sitting + microbursts of activity

Subjects rose from the seated position every hour for 6-hours from 0910 to 1430 to complete 5-minute bouts of moderate-intensity walking, yielding a total activity time of 30-minutes.

Group Type: EXPERIMENTAL

physical activity

Intervention Type: BEHAVIORAL

Interventions

physical activity

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

1. All ethnic groups and both genders

2. Age: Lower age limit: 19 years; Upper age limit: 45 years

3. Body-mass Index: Lower BMI limit: 18.5 kg/m2; Upper BMI limit: 29.9 kg/m2

4. Willing to adhere to caffeine restrictions of no more than two 16 ounce beverages in the morning of each study day with no caffeine intake after 12:00pm on any of the three study days

Exclusion Criteria

1. History of cardiovascular disease, including coronary artery disease, congestive heart failure, & unstable angina, or uncontrolled hypertension (>140/90 mm Hg)

2. Currently smoking or stopped smoking in the last 6 months

3. Medications affecting weight, energy intake, or energy expenditure in the last 6 months

4. Use of oral steroids

5. History of stroke or seizures, thyroid disease, type 1 or 2 diabetes, Cushing's syndrome, cerebrovascular, renal disease, hepatic disease, arrhythmias

6. Cancer requiring treatment in the past 5 years, with the exception of skin cancers other than melanoma

7. Infectious diseases: Self-reported HIV positivity or active tuberculosis

8. Inability to exercise for more than 30 minutes on a treadmill at moderate intensity

9. Currently pregnant, lactating or less than 6 months post-partum

10. History of a major psychiatric disorder including schizophrenia, bipolar illness or psychotic depression

11. Score of >25 on Beck Depression Inventory

12. No recreational drug use including marijuana in the past 1 year

• Minimum Eligible Age: 19 Years
• Maximum Eligible Age: 45 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Colorado, Denver

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

James Hill

Role: PRINCIPAL_INVESTIGATOR

University of Colorado, Denver

References

Bergouignan A, Legget KT, De Jong N, Kealey E, Nikolovski J, Groppel JL, Jordan C, O'Day R, Hill JO, Bessesen DH. Effect of frequent interruptions of prolonged sitting on self-perceived levels of energy, mood, food cravings and cognitive function. Int J Behav Nutr Phys Act. 2016 Nov 3;13(1):113. doi: 10.1186/s12966-016-0437-z.

Reference Type: DERIVED

PMID: 27809874 (View on PubMed)

Other Identifiers

13-2777

Identifier Type: -

Identifier Source: org_study_id