Medium Chain Triglycerides and Brain Metabolism in Alzheimer's Disease
NCT ID: NCT02709356
Last Updated: 2018-10-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
20 participants
INTERVENTIONAL
2015-10-31
2018-02-28
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Effect of MCT Emulsification on Ketogenesis in Human Adults
NCT02409927
Effect of Medium Chain Triglyceride Oil Supplementation in Mild Cognitive Impairment
NCT01669200
The Effect of Vegetable Oil on Cognitive Functions of MCI Patients
NCT03727386
Effect of Buglossoides Oil on Recent Chronic Non-injurious Hip and Knee Pain
NCT03576625
Clinical Trial to Study the Effects of Dietary Flax Beverage on Memory and Cognition
NCT04645927
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Alzheimer's disease
Patients with mild Alzheimer's disease.
1-month of 60-40 MCT oil and 1-month of C8 MCT oil (order of the two intervention are randomized)
1-month of 60-40 MCT oil
1-month supplementation of 30 g MCT oil (60% C10 + 40% C8)/day
1-month of C8 MCT oil
1-month supplementation of 30 g MCT oil (100% C8)/day (1-month of C8 MCT oïl)
Controls
Healthy elderly people
1-month of 60-40 MCT oil and 1-month of C8 MCT oil (order of the two intervention are randomized)
1-month of 60-40 MCT oil
1-month supplementation of 30 g MCT oil (60% C10 + 40% C8)/day
1-month of C8 MCT oil
1-month supplementation of 30 g MCT oil (100% C8)/day (1-month of C8 MCT oïl)
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
1-month of 60-40 MCT oil
1-month supplementation of 30 g MCT oil (60% C10 + 40% C8)/day
1-month of C8 MCT oil
1-month supplementation of 30 g MCT oil (100% C8)/day (1-month of C8 MCT oïl)
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Diagnosis of Alzheimer's disease (NINCDS-ADRDA criteria) for AD group
Exclusion Criteria
* Medical or psychiatric conditions that could interfere with study participation
* Fasting plasma glucose ≥7.0 mM (diabetes or prediabetes)
* Already on MCT supplementation
* Clinically-significant gastrointestinal disease/conditions
* Clinically-significant liver disease/dysfunction
* Clinically-significant renal disease/dysfunction
* Clinically-significant cardiac disease/conditions
* Hypertension
* Uncontrolled dyslipidaemia
* Vitamin B12 deficiency
* Structured physical activity (more than 3 times/week)
65 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Fondation Vitae
OTHER
Université de Sherbrooke
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Stephen Cunnane, PhD
Role: PRINCIPAL_INVESTIGATOR
Research Centre on Aging (CSSS-IUGS - CIUSSS de l'Estrie - CHUS) - Université de Sherbrooke
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Research Centre on Aging (CSSS-IUGS - CIUSSS de l'Estrie - CHUS)
Sherbrooke, Quebec, Canada
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2016-547
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.