Transversus Abdominus Plane Block in Living Donor Hepatectomy

NCT ID: NCT02708459

Last Updated: 2016-08-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-03-31

Study Completion Date

2016-08-31

Brief Summary

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Comparing different drugs used in Transversus abdominus plane analgesia after donor hepatectomy. Patients will be divided into three groups; control group, Bupivecaine group, and Dexmedetomedine group according to the used drug

Detailed Description

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Transversus abdominus plane block for postoperative analgesia after donor hpatectomy surgery using three different drugs control group, Bupivecaine group, and Dexmedetomedine group

Conditions

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Living Donor Hepatectomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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Control

Control group where postoperative analgesia will be maintained by Morphine intravenous boluses (2 mg) if Visual analogue scale (VAS) scale more than 4.

Group Type ACTIVE_COMPARATOR

Intravenous morphine

Intervention Type DRUG

Boluses of intravenous morphine (2 mg) will be given to patients if Visual analogue scale (VAS) more than 3

Bupevecaine group

Postoperative analgesia will be maintained by 20 ml Bupevecaine (0.25%) boluses in surgically inserted TAP catheter each 8 hours for 48 hours with rescue analgesia intravenous morphine (2mg) if VAS more than 4

Group Type ACTIVE_COMPARATOR

surgically inserted Transversus abdominus plane catheter

Intervention Type DEVICE

at end of surgery, a surgeon will insert catheter in Transversus abdominus plane (TAP) between internal oblique muscle and Transversus abdominus muscle

Intravenous morphine

Intervention Type DRUG

Boluses of intravenous morphine (2 mg) will be given to patients if Visual analogue scale (VAS) more than 3

Bupevecaine

Intervention Type DRUG

Dex group

catheter will surgically inserted in Transversus abdominus plane (TAP) plane before wound closure Postoperative analgesia will be maintained by Dexmedetomedine 0.4 mg/kg plus Bupevecaine 0.25 20 ml boluses each 8 hours for 48 hours in surgically inserted TAP catheter with rescue analgesia intravenous morphine (2mg) if VAS more 4

Group Type ACTIVE_COMPARATOR

surgically inserted Transversus abdominus plane catheter

Intervention Type DEVICE

at end of surgery, a surgeon will insert catheter in Transversus abdominus plane (TAP) between internal oblique muscle and Transversus abdominus muscle

Intravenous morphine

Intervention Type DRUG

Boluses of intravenous morphine (2 mg) will be given to patients if Visual analogue scale (VAS) more than 3

Bupevecaine

Intervention Type DRUG

Dexmedetomedine

Intervention Type DRUG

Interventions

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surgically inserted Transversus abdominus plane catheter

at end of surgery, a surgeon will insert catheter in Transversus abdominus plane (TAP) between internal oblique muscle and Transversus abdominus muscle

Intervention Type DEVICE

Intravenous morphine

Boluses of intravenous morphine (2 mg) will be given to patients if Visual analogue scale (VAS) more than 3

Intervention Type DRUG

Bupevecaine

Intervention Type DRUG

Dexmedetomedine

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* all living hepatectomy donors in Mansoura liver transplantation program

Exclusion Criteria

* refusal known sensetivity to used drugs
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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AlRefaey Kandeel

OTHER

Sponsor Role lead

Responsible Party

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AlRefaey Kandeel

Dr

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Mansoura university

Al Mansurah, Dakahlia Governorate, Egypt

Site Status

Mansoura university

Al Mansurah, Dkahleya, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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Abuelella TAP

Identifier Type: -

Identifier Source: org_study_id

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