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Measurement of Pulse Pressure Variation and Cardiac Output by a New Application for Android™ (Captesia™)

NCT ID: NCT02692222

Last Updated: 2016-12-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

57 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-02-29

Study Completion Date

2016-12-31

Brief Summary

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This study test the agreement and accuracy of Pulse Pressure Variation (PPV) and Cardiac Output (CO) obtained by the Android application Capstesia™ against the gold standard : PPV and CO calculated by thermodilution.

Detailed Description

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Pulse pressure variation (PPV) remains a good predictor of fluid responsiveness in the OR. However, PPV can be time-consuming to calculate (manual determination), is not always displayed on monitoring screens nor reliable through visual assessment and needs additional devices to be displayed. A new Android application (Captesia) automatically calculates the PPV utilizing a digital photograph of the arterial waveform from the monitor. The application determines the PPV by selecting peaks and troughs of the arterial curve.

Conditions

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Coronary Bypass

Keywords

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pulse pressure variation monitoring Captesia cardiac output monitoring

Study Design

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Study Time Perspective

PROSPECTIVE

Study Groups

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PPV

This study will track changes in PPV and CO before and after of volume expansion, which goal is to change the cardiac output.

Calculation of PPV and CO with two methods

Intervention Type OTHER

Interventions

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Calculation of PPV and CO with two methods

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patients scheduled for coronary artery bypass

Exclusion Criteria

* patients with arrhythmias like atrial fibrillation
* patients with valvular insufficiency
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Erasme University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Céline Boudart

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Céline F Boudart, MD

Role: PRINCIPAL_INVESTIGATOR

Erasme Hospital Bruxelles

Alexandre Joosten, MD

Role: PRINCIPAL_INVESTIGATOR

Erasme Hospital Bruxelles

Locations

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Erasme Hospital

Brussels, , Belgium

Site Status

Countries

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Belgium

References

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Yang X, Du B. Does pulse pressure variation predict fluid responsiveness in critically ill patients? A systematic review and meta-analysis. Crit Care. 2014 Nov 27;18(6):650. doi: 10.1186/s13054-014-0650-6.

Reference Type BACKGROUND
PMID: 25427970 (View on PubMed)

Cannesson M, Le Manach Y, Hofer CK, Goarin JP, Lehot JJ, Vallet B, Tavernier B. Assessing the diagnostic accuracy of pulse pressure variations for the prediction of fluid responsiveness: a "gray zone" approach. Anesthesiology. 2011 Aug;115(2):231-41. doi: 10.1097/ALN.0b013e318225b80a.

Reference Type BACKGROUND
PMID: 21705869 (View on PubMed)

Other Identifiers

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B406201526827

Identifier Type: -

Identifier Source: org_study_id