Three Different Oral Hygiene Regimes on Three Volatile Sulfur Compounds

NCT ID: NCT02689297

Last Updated: 2016-02-23

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: PHASE4
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2013-09-30
• Study Completion Date: 2013-11-30

Brief Summary

The purpose of the study is to evaluate the effect of various oral hygiene regimes on three volatile sulfur compounds.

Detailed Description

Thirty male monk volunteers who matched with the including criteria were divided randomly into two groups. Both groups were practiced to brush their teeth with scrubbing method for one week. Then, each group were instructed to do different additional protocol regimen- group A have to do mouth washing and tooth brushing and group B have to practice tongue cleaning addition to tooth brushing for three weeks. At the fifth week, both groups were instructed to practice tooth brushing, mouth washing and tongue cleaning. Three different volatile sulfur compounds were measured by oral chroma. Tongue characteristics, oral examination were checked as the outcomes of this study.

Conditions

Halitosis

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: SINGLE

Study Groups

group A

Mouthwash (chlorine dioxide 12ml two times per day, for three weeks)

Group Type: OTHER

chlorine dioxide

Intervention Type: OTHER

First week, subjects were instructed to do regular tooth brushing. After that group A was requested to use chlorine dioxide mouthwash two time per days for three weeks in addition to tooth brushing and then, one week for combination of tooth brushing, tongue cleaning and mouth washing.

group B

Small toothbrush for tongue cleaning two times per day for three weeks

Group Type: OTHER

small toothbrush for tongue cleaning

Intervention Type: OTHER

First week, subjects were instructed to do regular tooth brushing. After that group B was requested to brush their tongue with small toothbrush two time per days for three weeks in addition to tooth brushing and then, one week for combination of tooth brushing, tongue cleaning and mouth washing.

Interventions

chlorine dioxide

First week, subjects were instructed to do regular tooth brushing. After that group A was requested to use chlorine dioxide mouthwash two time per days for three weeks in addition to tooth brushing and then, one week for combination of tooth brushing, tongue cleaning and mouth washing.

Intervention Type: OTHER

small toothbrush for tongue cleaning

First week, subjects were instructed to do regular tooth brushing. After that group B was requested to brush their tongue with small toothbrush two time per days for three weeks in addition to tooth brushing and then, one week for combination of tooth brushing, tongue cleaning and mouth washing.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Clinical diagnosis of oral malodor
• No systemic diseases and no severe dental diseases
• At least 20 functional teeth

Exclusion Criteria

• Risky oral habit (smoking and betel quid chewing)
• Current use of antibiotics or any drugs
• Current use of any kind of mouthwash

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 30 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: Yes

Sponsors

Tokyo Medical and Dental University

OTHER

Sponsor Role: lead

Responsible Party

Ei Ei Aung

Graduate student, Department of Oral Health Promotion

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

OHP-018-EI-2

Identifier Type: -

Identifier Source: org_study_id