Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
150 participants
OBSERVATIONAL
2016-03-31
2026-02-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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Non-interventional
Eligibility Criteria
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Inclusion Criteria
2. Participant able and willing to give informed consent.
3. Clinical assessment demonstrates mechanical symptoms suggestive of meniscal pathology (focal knee pain +/- 1 or more of: catching/locking, giving way, focal joint-line tenderness, effusion, McMurray's positive) within last 12 months.
4. Evidence on clinical MRI knee of meniscal tear.
5. Participant is either in secondary care or has the potential to be referred to secondary care due to severity of symptoms.
6. Patient has failed conservative therapy and elected for surgical arthroscopic treatment, or is due knee drainage/injection for clinical reasons.
7. Competency of the English language to complete questionnaires independently.
Exclusion Criteria
2. Evidence of anterior cruciate ligament rupture, or more extensive soft tissue injury.
3. History of an acute knee injury (within 12 weeks), or acutely locked knee
4. Known history of inflammatory/septic arthritis of index knee.
5. Knee replacement or other non-arthroscopic knee surgery (e.g. high tibial osteotomy) - previous or planned within 1 year of study start.
6. Index knee surgery within last 3 months, including meniscectomy.
7. Steroid injection to index knee in last 3 months.
8. Active other (treated) inflammatory disease or infection.
9. Positive pregnancy test.
10. Unable to provide blood samples.
11. Unable to give informed written consent.
30 Years
60 Years
ALL
No
Sponsors
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Oxford University Hospitals NHS Trust
OTHER
University of Oxford
OTHER
Responsible Party
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Principal Investigators
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Fiona Watt, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Oxford
Locations
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Kennedy Insitute of Rheumatololgy, NDORMS, University of Oxford
Oxford, Oxfordshire, United Kingdom
Countries
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Related Links
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OA centre homepage
Other Identifiers
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PID 11499
Identifier Type: -
Identifier Source: org_study_id
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