Vitreous Inflammation in Standard and Heavy Silicone Oil
NCT ID: NCT02675543
Last Updated: 2017-06-02
Study Results
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View full resultsBasic Information
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COMPLETED
NA
70 participants
INTERVENTIONAL
2015-06-30
Brief Summary
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This situation is common in complicated retinal detachment, but is amplified after invasive surgery and by the use of intraocular tamponades that float over a subtle film of liquid where the inflammatory cytokines and growth factors reach the critical concentration over the inferior retina.
Many authors have noted that the heavy tamponade are more prone to cause intraocular inflammation compared to standard silicone oil, especially if they remain for several months in the eye.
The purpose of this study is to measure the vitreous concentration of some of the most important cytokines involved in the inflammatory vitreal response.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Standard silicone oil
after vitreous removal, the vitreous chamber was filled with standard silicone oil (PDMS)
Vitreous Tamponade with Silicone Oil
Heavy silicone oil
after vitreous removal, the vitreous chamber was filled with heavy silicone oil (Densiron 68)
Vitreous Tamponade with Silicone Oil
Interventions
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Vitreous Tamponade with Silicone Oil
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* uveitis
18 Years
ALL
No
Sponsors
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Università degli Studi di Brescia
OTHER
Responsible Party
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Francesco Semeraro
To Compare Vitreous Inflammation in Standard Versus Heavy Silicone Oil
References
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Schwartz SG, Flynn HW Jr, Wang X, Kuriyan AE, Abariga SA, Lee WH. Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy. Cochrane Database Syst Rev. 2020 May 13;5(5):CD006126. doi: 10.1002/14651858.CD006126.pub4.
Other Identifiers
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Vitreo002
Identifier Type: -
Identifier Source: org_study_id
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