Integrated Treatment for Posttraumatic Stress Disorder and Substance Abuse in Young Adults

NCT ID: NCT02667119

Last Updated: 2022-09-22

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

27 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-04-30

Study Completion Date

2021-06-16

Brief Summary

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The purpose of the study is to determine the safety and efficacy of an integrated treatment for substance abuse and posttraumatic stress disorder for young adults. The integrated treatment includes two established psychosocial treatments for substance abuse (Contingency Management) and posttraumatic stress disorder (Prolonged Exposure therapy).

Detailed Description

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Conditions

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Substance Use Disorder Posttraumatic Stress Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Prolonged Exposure + Contingency Management

Standard services plus Prolonged Exposure and Contingency Management

Group Type EXPERIMENTAL

Prolonged Exposure with Contingency Management

Intervention Type BEHAVIORAL

Prolonged Exposure therapy for posttraumatic stress disorder includes psychoeducation, breathing retraining, in vivo exposure, and imaginal exposure.

Contingency Management for substance abuse disorders: participants will have the chance to win prizes for each negative urine drug screen/breathalyzer provided.

Standard Care

Intervention Type BEHAVIORAL

Standard care will consist of treatment as usual in a community-based substance use treatment center.

Standard Care

Standard substance abuse treatment services

Group Type ACTIVE_COMPARATOR

Standard Care

Intervention Type BEHAVIORAL

Standard care will consist of treatment as usual in a community-based substance use treatment center.

Interventions

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Prolonged Exposure with Contingency Management

Prolonged Exposure therapy for posttraumatic stress disorder includes psychoeducation, breathing retraining, in vivo exposure, and imaginal exposure.

Contingency Management for substance abuse disorders: participants will have the chance to win prizes for each negative urine drug screen/breathalyzer provided.

Intervention Type BEHAVIORAL

Standard Care

Standard care will consist of treatment as usual in a community-based substance use treatment center.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 18-25 years old
* meets diagnostic criteria for substance use disorder
* meets diagnostic criteria for full or subthreshold posttraumatic stress disorder
* currently able to provide a urine drug screen that is negative for cocaine, prescription opiates, and non-prescribed methadone or provided this type of screen in the past 60 days
* speaks English

Exclusion Criteria

* significant cognitive impairment or serious uncontrolled psychiatric problem (other than posttraumatic stress disorder)
* in recovery from pathological gambling or current pathological gambling diagnosis
* in a current domestic violence relationship
Minimum Eligible Age

18 Years

Maximum Eligible Age

25 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role collaborator

UConn Health

OTHER

Sponsor Role lead

Responsible Party

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Kristyn Zajac

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kristyn Zajac, PhD

Role: PRINCIPAL_INVESTIGATOR

UConn Health

Locations

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UConn Health

Farmington, Connecticut, United States

Site Status

The Village for Families and Children - Adult Services

Hartford, Connecticut, United States

Site Status

Farrell Treatment Center

New Britain, Connecticut, United States

Site Status

Countries

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United States

References

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Zajac K, Sheidow AJ, Davis M. Juvenile Justice, Mental Health, and the Transition to Adulthood: A Review of Service System Involvement and Unmet Needs in the U.S. Child Youth Serv Rev. 2015 Sep 1;56:139-148. doi: 10.1016/j.childyouth.2015.07.014.

Reference Type BACKGROUND
PMID: 26273119 (View on PubMed)

Zajac K, Randall J, Swenson CC. Multisystemic Therapy for Externalizing Youth. Child Adolesc Psychiatr Clin N Am. 2015 Jul;24(3):601-16. doi: 10.1016/j.chc.2015.02.007. Epub 2015 Mar 29.

Reference Type BACKGROUND
PMID: 26092742 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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K23DA034879

Identifier Type: NIH

Identifier Source: secondary_id

View Link

16-101-2

Identifier Type: -

Identifier Source: org_study_id

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