Adaptive Treatment for Adolescent Cannabis Use Disorders

NCT ID: NCT01656707

Last Updated: 2017-04-11

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 172 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2011-09-30
• Study Completion Date: 2016-07-31

Brief Summary

The purpose of this study is to examine an Adaptive Treatment approach in order to improve outcomes of youth with Cannabis Use Disorders who are poor responders to treatment.

Detailed Description

The study will address the current contrasts in youth response to treatment, the problem of poor response to treatment and the prevention of relapse. Results from the study may support Adaptive Treatment as an efficacious approach for youth with Cannabis Use Disorder who are poor responders to treatment.

Poor responders fall into two categories, those who failed to achieve a negative drug urinalysis during the last session of the initial MET/CBT-7 treatment they attended, and those who either dropped out or were administratively discharged at any time during the initial MET/CBT-7 treatment.

Conditions

Mental Disorders; Addictive Behaviors; Cannabis Use Disorder

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

ACRA

Ten weekly 60-minute sessions of Adolescent Community Reinforcement Approach (ACRA) will be provided as an Adaptive treatment condition.

Group Type: EXPERIMENTAL

ACRA

Intervention Type: BEHAVIORAL

Ten weekly,60-minute therapy sessions including six individual, two parent/guardian and two joint (individual and parent/guardian).

Cognitive Behavioral Therapy (CBT)

Ten weekly, 60-minute sessions of augmented individualized Cognitive Behavioral Therapy (CBT)will be provided as an Adaptive Treatment condition

Group Type: EXPERIMENTAL

CBT

Intervention Type: BEHAVIORAL

10 weekly, 60-minute sessions of augmented individualized CBT

Interventions

ACRA

Ten weekly,60-minute therapy sessions including six individual, two parent/guardian and two joint (individual and parent/guardian).

Intervention Type: BEHAVIORAL

CBT

10 weekly, 60-minute sessions of augmented individualized CBT

Intervention Type: BEHAVIORAL

Other Intervention Names

Adolescent Community Reinforcement Approach; Cogntive Behavioral Therapy

Eligibility Criteria

Inclusion Criteria

• 13-18 years of age at the time of intake assessment
• Current diagnosis of DSM-IV Cannabis Abuse or Dependence
• Able to read and comprehend English at a 5th grade level
• Residence within 45 minutes drive from the UCHC Farmington treatment site
• Participant and a parent/legal guardian responsible for providing collateral information agree to sign an IRB approved consent form
• Participant and a parent/legal guardian responsible for providing collateral information agree to provide locator information
• The family is not planning to move from the area during the next six months

Exclusion Criteria

• Meet criteria for dependence of any other substance of abuse other than nicotine or alcohol
• Report suicidal ideation with a plan, suicidal behavior, a plan to hurt oneself or other, or a history of self-injurious behavior all occurring in the last 30 days
• Meet a lifetime diagnosis of schizophrenia
• Has any current health (i.e. medical, psychiatric) condition that will compromise the participant's ability to regularly attend treatment
• Demonstrate an inability or unwillingness to provide locator information

• Minimum Eligible Age: 13 Years
• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role: collaborator

UConn Health

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Yifrah Kaminer, MD, MBA

Role: PRINCIPAL_INVESTIGATOR

UConn Health

Locations

University of Connecticut Health Center

Farmington, Connecticut, United States

Countries

United States

Other Identifiers

R01DA030454

Identifier Type: NIH

Identifier Source: secondary_id

View Link

PA08-263

Identifier Type: -

Identifier Source: org_study_id