Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
834 participants
OBSERVATIONAL
2016-01-01
2018-01-18
Brief Summary
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Sarcopenia is defined by a loss of muscle mass, loss of muscle strength and loss of muscle quality. It is a geriatric syndrome that, to this date, is not systematically tracked in clinical practice.
In order to detect sarcopenia, the investigators will use the operational definition proposed by the European Working Group (EWGSOP) involving the measure of three parameters, namely the speed of walking, the muscle strength and the measurement of the muscular mass.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Geriatric ward population
Every patient aged over 65 admitted in the unit 83 of the Geriatry Department, CHU Brugmann Hospital, undergoes a global geriatric evaluation at the end of its hospitalisation stay, including sarcopenia detection.
Sarcopenia detection
The assessment of sarcopenia is performed according to the recommendations of the EWGSOP (European Working Group on Sarcopenia in Older people). Three measurements are made:
* Muscle mass measurement by dual energy X-ray absorptiometry (DEXA).
* Walking speed measurement
* Hand grip test
A diagnosis of sarcopenia is established if the walking speed is inferior to 0.8 m/sec, the muscular strength is low and the muscular mass is low.
Data regarding the geriatric characteristics of this sarcopenic population will be collected.
Interventions
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Sarcopenia detection
The assessment of sarcopenia is performed according to the recommendations of the EWGSOP (European Working Group on Sarcopenia in Older people). Three measurements are made:
* Muscle mass measurement by dual energy X-ray absorptiometry (DEXA).
* Walking speed measurement
* Hand grip test
A diagnosis of sarcopenia is established if the walking speed is inferior to 0.8 m/sec, the muscular strength is low and the muscular mass is low.
Data regarding the geriatric characteristics of this sarcopenic population will be collected.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Patients unable to perform the hand- grip test, the walk test or measurement of the body components by DEXA
* Patients in severe pain
* Bedridden patients
* Patients for which a clear therapeutic abstention has been established
* Language barriere that cannot be overcome
* Patients unable to walk without the help of a third person
65 Years
ALL
No
Sponsors
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Brugmann University Hospital
OTHER
Responsible Party
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Murielle Surquin
Head of clinic
Principal Investigators
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Robin Barré, MD
Role: PRINCIPAL_INVESTIGATOR
CHU Brugmann
Murielle Surquin, MD
Role: PRINCIPAL_INVESTIGATOR
CHU Brugmann
Florence Benoît, MD
Role: PRINCIPAL_INVESTIGATOR
CHU Brugmann
Marie Claessens, MD
Role: PRINCIPAL_INVESTIGATOR
CHU Brugmann
Locations
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CHU Brugmann
Brussels, , Belgium
Countries
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References
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Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinkova E, Vandewoude M, Zamboni M; European Working Group on Sarcopenia in Older People. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010 Jul;39(4):412-23. doi: 10.1093/ageing/afq034. Epub 2010 Apr 13.
Baumgartner RN, Koehler KM, Gallagher D, Romero L, Heymsfield SB, Ross RR, Garry PJ, Lindeman RD. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol. 1998 Apr 15;147(8):755-63. doi: 10.1093/oxfordjournals.aje.a009520.
Cesari M, Kritchevsky SB, Newman AB, Simonsick EM, Harris TB, Penninx BW, Brach JS, Tylavsky FA, Satterfield S, Bauer DC, Rubin SM, Visser M, Pahor M; Health, Aging and Body Composition Study. Added value of physical performance measures in predicting adverse health-related events: results from the Health, Aging And Body Composition Study. J Am Geriatr Soc. 2009 Feb;57(2):251-9. doi: 10.1111/j.1532-5415.2008.02126.x.
Lauretani F, Russo CR, Bandinelli S, Bartali B, Cavazzini C, Di Iorio A, Corsi AM, Rantanen T, Guralnik JM, Ferrucci L. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J Appl Physiol (1985). 2003 Nov;95(5):1851-60. doi: 10.1152/japplphysiol.00246.2003.
Other Identifiers
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CHUB-sarcopenia
Identifier Type: -
Identifier Source: org_study_id
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