Interpretation Bias Modification for Body Dysmorphic Disorder

NCT ID: NCT02635152

Last Updated: 2021-01-29

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 50 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2015-09-30
• Study Completion Date: 2018-03-31

Brief Summary

The purpose of this study is to determine whether a computerized intervention designed to reduce appearance and evaluation related interpretation biases will reduce symptoms associated with body dysmorphic disorder.

Detailed Description

The present study aims to examine the feasibility of a remote treatment for body dysmorphic disorder delivered via the Internet. To evaluate the efficacy of the IBM protocol we have developed in reducing negative appearance and evaluative related interpretations, we will conduct a two-arm randomized controlled trial over the internet. Individuals with a diagnosis of body dysmorphic disorder (N = 40) will be randomized to one of two conditions: 1) IBM or 2) progressive muscle relaxation. Each condition will consist of eight 10-25 minute treatment sessions. Participants will complete two sessions per week for four weeks and will be administered assessments at pre-treatment, one week post-treatment and at 3-month follow-up. We hypothesize that: 1) IBM will lead to greater reductions in BDD symptoms than the PMR condition; 2) IBM will lead to greater reductions in depression, anxiety and suicidal ideation than the PMR condition; 3) IBM will lead to greater reductions in threat interpretations and greater increases in benign interpretations than the PMR condition; 4) The effects of condition on BDD symptoms will be mediated by changes in BDD-related interpretation bias; and 5) The effects of training in the IBM condition will be maintained at the 3-month follow-up assessments.

Conditions

Body Dysmorphic Disorder

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Interpretation Bias Modification (IBM)

Treatment consists of eight brief sessions. In Task 1, participants read unique scenarios ("You notice someone pointing in your direction"). A sentence meant to resolve the ambiguity will appear ("This person thinks they reco\_nize you"). After filling in the missing letter, the interpretation is reinforced by requiring the participants to correctly answer "yes" or "no" to a comprehension question ("Is this person mocking you?"). In Task 2, participants are shown a word denoting a threatening ("mocking") or benign ("cheerful") interpretation. Participants are presented with an ambiguous scenario ("You hear people at a nearby table laughing") and asked to denote whether the word and the sentence are related. Participants will receive positive or negative feedback based on their response.

Group Type: EXPERIMENTAL

Interpretation Bias Modification

Intervention Type: BEHAVIORAL

Eight 10-25 minute sessions of interpretation modification to reduce negative interpretation biases related to appearance.

Progressive Muscle Relaxation (PMR)

Participants will receive eight brief sessions of PMR. They will listen to a PMR script (Kassinove \& Tafrate, 2002). Participants will be asked to make sure they are sitting comfortably, close their eyes, and systematically tense and release 10 different muscle groups.

Group Type: ACTIVE_COMPARATOR

Progressive Muscle Relaxation

Intervention Type: BEHAVIORAL

Eight 15-minute sessions of progressive muscle relaxation (PMR).

Interventions

Interpretation Bias Modification

Eight 10-25 minute sessions of interpretation modification to reduce negative interpretation biases related to appearance.

Intervention Type: BEHAVIORAL

Progressive Muscle Relaxation

Eight 15-minute sessions of progressive muscle relaxation (PMR).

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Current diagnosis of Body Dysmorphic Disorder according to DSM-5 criteria
• BDD-YBOCS score greater than or equal to 20
• Fluent in English
• No significant physical defect or flaw in appearance (e.g., disfiguration)

Exclusion Criteria

• History of psychotic disorder, bipolar disorder, borderline personality disorder
• Current substance use disorder
• Unstable medication status (i.e. change in medication within the last month)
• Concurrent psychotherapy for appearance concerns
• Active and clinically significant suicidality

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Florida State University

OTHER

Sponsor Role: lead

Responsible Party

Jesse Cougle

Associate Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Natalie L. Matheny, BA

Role: PRINCIPAL_INVESTIGATOR

Florida State University

Locations

Florida State University Psychology Department

Tallahassee, Florida, United States

Countries

United States

References

Wilver NL, Cougle JR. An Internet-based controlled trial of interpretation bias modification versus progressive muscle relaxation for body dysmorphic disorder. J Consult Clin Psychol. 2019 Mar;87(3):257-269. doi: 10.1037/ccp0000372. Epub 2018 Dec 27.

Reference Type: DERIVED

PMID: 30589349 (View on PubMed)

Other Identifiers

2017.20244

Identifier Type: -

Identifier Source: org_study_id