AUgmented REality for the Visually Impaired - Part 1

NCT ID: NCT02614651

Last Updated: 2017-07-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-05-31

Study Completion Date

2017-05-29

Brief Summary

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The main objective of this study is to quantify vision parameters in subjects with concentric visual field constriction, and this in relation to the display on virtual reality goggles. More specifically:

* The maximum brightness value for visual comfort (THRESHOLD\_MAX)
* The minimum value of the perceptible light contrast in low light perceptible (THRESHOLD\_MIN)
* The speed of light change adaptation in the range \[THRESHOLD\_MAX-THRESHOLD\_MIN\] and \[THRESHOLD\_MIN-THRESHOLD\_MAX\].

Detailed Description

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Secondary objectives are to:

A. Quantifying the device parameters "RV glasses + camera" depending on visual acuity and the visual field of each subject:

* Optimal extent of the visual field provided by the device "RV glasses + camera".

B. Measuring the effectiveness of different image processing algorithms used in the development of the software part of this technical assist device:

* Capture and display HDR images (High Dynamic Range)
* Color adjustment.

Conditions

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Retinitis Pigmentosa Glaucoma

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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The study population

The study population consists of subjects with a concentric constriction of the visual field (retinitis pigmentosa, glaucoma) whose motor capacity allows the use of a computer keyboard with one hand. Subjects are recruited on a voluntary basis, from information disseminated to professionals in the rehabilitation of functional low vision and patient associations, in the Ophthalmology Service of the University Hospital of Nimes and within the ARAMAV Institute.

Intervention: Find visual comfort threshold related to light intensity

Intervention: Find the size of the visual field

Intervention: Effectiveness of brightness control

Intervention: Performance of color correction

Intervention: Vuzix Wrap 1200DX virtural reality glasses

Group Type EXPERIMENTAL

Find visual comfort threshold related to light intensity

Intervention Type PROCEDURE

In this testing session, the patient's visual comfort threshold related to light intensity will be determined. Test sessions are kept under 45 minutes.

The subject is sitting in front of a keyboard and a computer screen. He/she is invited to recognize letters successively displayed in the center of the screen, this center is marked with a black cross. Each letter appearance is preceded by a beep. The subject must click on the "space" bar on the keyboard as soon as he/she recognizes the letter, then gives his/her answer orally.

Find the size of the visual field

Intervention Type PROCEDURE

For these tests, the subject is seated at a table, 1.5m from a wall. It features a computer keyboard. It projects an image on the wall, using to a video projector. An image moving towards a target (along 16 different trajectories) is used to evaluate the size of the visual field.

Effectiveness of brightness control

Intervention Type PROCEDURE

During this testing session, the investigators seek to evaluate the effectiveness of the algorithms used to control the brightness.

The subject is in a room with four different computers. The subject is asked to identify the objects displayed on different computer monitors in the room: he/she must press a key on the keyboard when he/she detects an object and state aloud the nature of the object.

Performance of color correction

Intervention Type PROCEDURE

During this session, the investigators try to assess the performance for the color vision correction (saturation and hue).

The subject, while wearing the virtual reality glasses + camera performs a test (twice) that requires matching colored dots (i.e. a Farnsworth test) under controlled light conditions.

Vuzix Wrap 1200DX virtural reality glasses

Intervention Type DEVICE

The other interventions are performed with the use of virtual reality glasses, specifically the Vuzix Wrap 1200DX. In case of technical difficulties, the latter can be swapped with the Oculus Rift model or another model. The associated webcameras are from Logitech, and the exact model used can vary and does not carry any importance for this research.

Interventions

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Find visual comfort threshold related to light intensity

In this testing session, the patient's visual comfort threshold related to light intensity will be determined. Test sessions are kept under 45 minutes.

The subject is sitting in front of a keyboard and a computer screen. He/she is invited to recognize letters successively displayed in the center of the screen, this center is marked with a black cross. Each letter appearance is preceded by a beep. The subject must click on the "space" bar on the keyboard as soon as he/she recognizes the letter, then gives his/her answer orally.

Intervention Type PROCEDURE

Find the size of the visual field

For these tests, the subject is seated at a table, 1.5m from a wall. It features a computer keyboard. It projects an image on the wall, using to a video projector. An image moving towards a target (along 16 different trajectories) is used to evaluate the size of the visual field.

Intervention Type PROCEDURE

Effectiveness of brightness control

During this testing session, the investigators seek to evaluate the effectiveness of the algorithms used to control the brightness.

The subject is in a room with four different computers. The subject is asked to identify the objects displayed on different computer monitors in the room: he/she must press a key on the keyboard when he/she detects an object and state aloud the nature of the object.

Intervention Type PROCEDURE

Performance of color correction

During this session, the investigators try to assess the performance for the color vision correction (saturation and hue).

The subject, while wearing the virtual reality glasses + camera performs a test (twice) that requires matching colored dots (i.e. a Farnsworth test) under controlled light conditions.

Intervention Type PROCEDURE

Vuzix Wrap 1200DX virtural reality glasses

The other interventions are performed with the use of virtual reality glasses, specifically the Vuzix Wrap 1200DX. In case of technical difficulties, the latter can be swapped with the Oculus Rift model or another model. The associated webcameras are from Logitech, and the exact model used can vary and does not carry any importance for this research.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* The patient must have given his/her informed and signed consent
* The patient must be insured or beneficiary of a health insurance plan
* The subject is suffering from retinitis pigmentosa or glaucoma with concentric visual field constriction and presents with:
* An acuity in the better eye superior or equal to 1/10 in near vision,
* A binocular field of between 1° and 30°,
* A good central fixation, absence of central scotoma,
* Motor capability for using a computer keyboard with one hand.

Exclusion Criteria

* The patient is participating in another study
* The patient is in an exclusion period determined by a previous study
* The patient is under judicial protection, or under guardianship
* The patient refuses to sign the consent
* It is impossible to correctly inform the patient
* Subjects with (or evolving toward) a multiple sensory disability, or one including cognitive disorders
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Nīmes

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Isabelle Marc, PhD

Role: STUDY_DIRECTOR

Laboratoire LGI2P, Ecole Nationale Supérieure des Mines

Luc Jeanjean, MD

Role: PRINCIPAL_INVESTIGATOR

Centre Hospitalier Universitaire de Nîmes

Locations

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CHRU de Nîmes - Hôpital Universitaire Carémea

Nîmes, , France

Site Status

Countries

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France

Other Identifiers

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2016-A00099-42

Identifier Type: OTHER

Identifier Source: secondary_id

LOCAL/2015/IMGD-01

Identifier Type: -

Identifier Source: org_study_id

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