Impact of a Pluriprofessional Intervention to Improve Medication Adherence (Secondary Preventive Medication) in Patients After Ischemic Stroke
NCT ID: NCT02611440
Last Updated: 2019-12-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
182 participants
INTERVENTIONAL
2015-07-29
2020-07-28
Brief Summary
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A patient - centered and pluriprofessional structured intervention, targeting the medication, introduced at hospital discharge and continued at home (by regular telephone contact) could improve medication adherence one year after stroke.
This intervention would consist of semi structured interviews patient-pharmacist at different times during one year after stroke. The information about the therapeutic management of the patient will be shared between healthcare professionals : general practitioners (GP) and community pharmacists (CP), hospital clinical pharmacist (HCP) and physician (HPhys).
It will allow for decrease of the recurrent stroke and others cardiovascular complications based on a better adherence to preventive medication. Furthermore the decrease of the iatrogenic events and the improvement of the quality of life of patients may be also associated.
Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
NONE
Study Groups
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Pharmacist Intervention
It will be a semi -structured interviews with patient and pharmacist over various time after the stroke (at Month0, M3, M6, M9) combined with patient's therapeutic follow-up from various healthcare professionals.
Pharmaceutical care
Initial interview with pharmacist (at the hospital discharge): Evaluation aimed to identify barriers to adherence to drug treatment followed by an information session on the disease, the benefit of drugs and the importance of diet and lifestyle habits. Pharmacist advices focused on how to take medication and how to manage adverse events will be provided.
Telephone interviews with hospital clinical pharmacist - patient (at M3 M6 and M9): The objective is to review with the patient its medication-taking routine and its potential difficulties, to motivate adherence to treatment and lifestyle/dietary rules, to give advices about therapeutics and how to take medication.
HCP contacts CP to determine the prescription refill. Final interview with HCP pharmacist (at M12): The objective is to take stock with the patient about its taking drug load.
Control
No pharmacist intervention planned.
No interventions assigned to this group
Interventions
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Pharmaceutical care
Initial interview with pharmacist (at the hospital discharge): Evaluation aimed to identify barriers to adherence to drug treatment followed by an information session on the disease, the benefit of drugs and the importance of diet and lifestyle habits. Pharmacist advices focused on how to take medication and how to manage adverse events will be provided.
Telephone interviews with hospital clinical pharmacist - patient (at M3 M6 and M9): The objective is to review with the patient its medication-taking routine and its potential difficulties, to motivate adherence to treatment and lifestyle/dietary rules, to give advices about therapeutics and how to take medication.
HCP contacts CP to determine the prescription refill. Final interview with HCP pharmacist (at M12): The objective is to take stock with the patient about its taking drug load.
Eligibility Criteria
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Inclusion Criteria
* Patient with ischemic stroke hospitalized in physical medicine and rehabilitation unit or neurovascular unit
* Return at home at the hospital discharge
* Medication including an antiplatelet drug or an oral anticoagulant with at least an antihypertensive drug and/or a lipid lowering agent (statin)
* Patient without either cognitive disorders or major psychiatric disorders
* Patient with a sufficient autonomy for the management of medication at home (score of Barthel \> 30)
Exclusion Criteria
* Patient with important cognitive or psychiatric disorders
* Management of patient medication exclusively by the helper
* No usual pharmacy (or more than 2 usual pharmacies)
* Patient directed to an institution at the end of the hospitalization
18 Years
ALL
No
Sponsors
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Hospices Civils de Lyon
OTHER
Responsible Party
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Locations
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Service de neurologie vasculaire, Hôpital P Wertheimer, HCL
Bron, , France
Service de médecine physique et de réadaptation, Hôpital Nord, CHU de Clermont Ferrand
Cébazat, , France
Service de médecine physique et de réadaptation, Hôpital sud, CHU de Grenoble
Échirolles, , France
Service de médecine physique et de réadaptation, Groupe hospitalier Lariboisière - Fernand Vidal, AP-HP
Paris, , France
Service de médecine physique et de réadaptation, Hôpital Bellevue, CHU Saint Etienne
Saint-Etienne, , France
Service de médecine physique et de réadaptation, Hôpital Henry Gabrielle, Groupement Hospitalier Sud, HCL
Saint-Genis-Laval, , France
Countries
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Central Contacts
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Facility Contacts
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Norbert NIGHOGHOSSIAN, MD
Role: primary
Emmanuel COUDEYRE, MD
Role: primary
Dominique PERENNOU, MD
Role: primary
Alain YELNIK, MD
Role: primary
Pascal GIRAUX, MD
Role: primary
Gilles RODE, MD
Role: primary
References
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Khettar S, Jacquin Courtois S, Luaute J, Decullier E, Bin S, Dupuis M, Derex L, Mechtouff L, Nighoghossian N, Dussart C, Rode G, Janoly-Dumenil A. Multiprofessional intervention to improve adherence to medication in stroke patients: a study protocol for a randomised controlled trial (ADMED AVC study). Eur J Hosp Pharm. 2022 May;29(3):169-175. doi: 10.1136/ejhpharm-2020-002425. Epub 2020 Sep 25.
Other Identifiers
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2014.859
Identifier Type: -
Identifier Source: org_study_id