Effectiveness of Cortiment® in Patients With Ulcerative Colitis

NCT ID: NCT02586259

Last Updated: 2019-11-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

378 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-12-31

Study Completion Date

2018-04-05

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to evaluate Cortiment® with regard to its use by clinicians in routine clinical practice and its effectiveness and tolerability in a real-life setting.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Ulcerative Colitis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Cortiment®

Treatment according to routine clinical practice.

budesonide MMX®

Intervention Type DRUG

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

budesonide MMX®

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Cortiment®

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Men and women aged ≥ 18 years
* Outpatients
* Patients who have been prescribed Cortiment® for the treatment of mild to moderate active ulcerative colitis within a 5 days' time window prior to being included in the study
* Patients who have received adequate information regarding this non-interventional study and are able to understand and voluntarily sign the Informed Consent

Exclusion Criteria

* Patients with severe active / fulminant ulcerative colitis
* Patients treated with antibiotics or corticosteroids for the current flare. Use of Antibiotics for other conditions non-related to the gastrointestinal tract, either before enrolment or during the observational period is permitted.
* History of total / sub-total colectomy
* Hypersensitivity to the active substance, lecithin (derived soya oil, peanut oil) or to any of the excipients
* Patients enrolled and involved in an interventional study
* Patients whom investigators consider inappropriate to participate in the study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Ferring Pharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Global Clinical Compliance

Role: STUDY_DIRECTOR

Ferring Pharmaceuticals

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Digestive Health Clinic (there may be other sites in this country)

Richmond Hill, , Canada

Site Status

Magen-Darm-Zentrum, Facharztzentrum Eppendorf (there may be other sites in this country)

Hamburg, , Germany

Site Status

St. Vincent's University Hospital (there may be other sites in this country)

Dublin, , Ireland

Site Status

Investigational site (there may be other sites in this country)

Bologna, , Italy

Site Status

Investigational site (there may be other sites in this country)

Amsterdam, , Netherlands

Site Status

Investigational site (there may be other sites in this country)

Warsaw, , Poland

Site Status

Danderyds sjukhus (there may be other sites in this country)

Stockholm, , Sweden

Site Status

Kings College Hospital (there may be other sites in this country)

London, , United Kingdom

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Canada Germany Ireland Italy Netherlands Poland Sweden United Kingdom

References

Explore related publications, articles, or registry entries linked to this study.

Danese S, Hart A, Dignass A, Fiorino G, Louis E, Bonovas S, D'Haens G, Dotan I, Rogler G, Paridaens K, Peyrin-Biroulet L. A multicentre prospective cohort study assessing the effectiveness of budesonide MMX(R) (Cortiment(R)MMX(R)) for active, mild-to-moderate ulcerative colitis. United European Gastroenterol J. 2019 Nov;7(9):1171-1182. doi: 10.1177/2050640619864848. Epub 2019 Jul 17.

Reference Type RESULT
PMID: 31700630 (View on PubMed)

Danese S, Hart A, Dignass A, Louis E, D'Haens G, Dotan I, Rogler G, D'Agay L, Iannacone C, Peyrin-Biroulet L. Effectiveness of budesonide MMX (Cortiment) for the treatment of mild-to-moderate active ulcerative colitis: study protocol for a prospective multicentre observational cohort study. BMJ Open Gastroenterol. 2016 May 17;3(1):e000092. doi: 10.1136/bmjgast-2016-000092. eCollection 2016.

Reference Type DERIVED
PMID: 27239329 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

000217

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.