Microbiota Community of Irritable Bowel Syndrome in Episodes and Remission Phase

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-07-31

Study Completion Date

2015-11-30

Brief Summary

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Analyze microbiota community of irritable bowel syndrome in episodes phase and remission phase.

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Detailed Description

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The pathophysiology of IBS is incompletely understood, it may involve an altered intestinal microbiota. Since the microflora composition of IBS is various in different studies, The investigators plan to compare the intestinal microbiota of IBS patients in episodes phase and remission phase with healthy controls,trying to find the difference.

Conditions

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Irritable Bowel Syndrome

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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IBS patients in episodes phase

collect faeces from IBS patients in episodes remission phase

collect faeces from participants

Intervention Type OTHER

analyze the fecal microbiota community using 16S rDNA detection technique

IBS patients in remission phase

collect faeces from IBS patients in remission phase

collect faeces from participants

Intervention Type OTHER

analyze the fecal microbiota community using 16S rDNA detection technique

healthy controls

collect faeces from healthy controls

collect faeces from participants

Intervention Type OTHER

analyze the fecal microbiota community using 16S rDNA detection technique

Interventions

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collect faeces from participants

analyze the fecal microbiota community using 16S rDNA detection technique

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* the presence of Rome III criteria for IBS ;
* Patients scheduled for colonoscopy examination or having negative screening examinations
* Aged between 18 and 65 years old

Exclusion Criteria

* Antibiotic, probiotic or laxative usage within 4 weeks.
* organic gastrointestinal diseases
* Severe systematic disease: diabetes mellitus, hepatic, renal or cardiac dysfunction, thyroid disease or tumor etc.
* pregnancy or lactation.
* previous major or complicated abdominal surgery.
* severe endometriosis and dementia

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes