Post-Approval Study of the Tecnis® Toric IOL

NCT ID: NCT02566083

Last Updated: 2020-01-18

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

365 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-10-21

Study Completion Date

2019-05-23

Brief Summary

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This study is a prospective, multicenter, bilateral, non-randomized, open-label, comparative clinical study conducted at up to 80 sites in the USA. Subjects will choose to be bilaterally implanted with either 1) the TECNIS 1-Piece Toric IOLs, Model ZCT300 and/or ZCT400, or 2) the TECNIS Monofocal Model ZCB00 non-toric control IOL, according to subject preference

Detailed Description

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Conditions

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Cataract

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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non-toric intraocular lens

non-toric approved intraocular lens

Group Type ACTIVE_COMPARATOR

non-toric intraocular lens

Intervention Type DEVICE

TECNIS One-piece Monofocal Model ZCB00

toric intraocular lens

approved toric intraocular lens

Group Type ACTIVE_COMPARATOR

toric intraocular lens

Intervention Type DEVICE

TECNIS One-piece Toric Models ZCT300 or ZCT400

Interventions

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non-toric intraocular lens

TECNIS One-piece Monofocal Model ZCB00

Intervention Type DEVICE

toric intraocular lens

TECNIS One-piece Toric Models ZCT300 or ZCT400

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Minimum 22 years of age
* Bilateral cataracts
* Preoperative keratometric cylinder in both eyes
* Most appropriate toric IOL model choice (ZCT300 or ZCT400)
* Predicted residual refractive cylinder, based on the AMO Toric IOL Calculator, must be:

≤ 0.69 D for a ZCT300 IOL or ≤ 0.88 D for a ZCT400 IOL
* Clear intraocular media other than cataract in each eye
* Availability, willingness, ability and sufficient cognitive awareness to comply with examination procedures and study visits
* Ability to understand, read and write English in order to consent to study participation and complete a study questionnaire
* Signed informed consent and HIPAA authorization

Exclusion Criteria

* Irregular corneal astigmatism
* Any corneal pathology/abnormality other than regular corneal astigmatism
* Previous corneal surgery
* Recent ocular trauma or intraocular surgery that is not resolved/stable or may affect visual outcomes
* Any pupil abnormalities
* Subjects with conditions associated with increased risk of zonular rupture, including capsular or zonular abnormalities that may lead to IOL decentration, including pseudoexfoliation, trauma, or posterior capsule defects
* Known ocular disease or pathology that may affect visual acuity or that may require surgical intervention during the course of the study
* Concurrent participation or participation during 30 days prior to preoperative visit in any other clinical study
* Planned monovision correction
* Patient is pregnant, plans to become pregnant, is lactating or has another condition associated with the fluctuation of hormones that could lead to refractive changes
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abbott Medical Optics

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Devi Priya Janakiraman, OD, FAAO

Role: STUDY_DIRECTOR

Johnson & Johnson Surgical Vision

Locations

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Eye Center South

Dothan, Alabama, United States

Site Status

Arizona Eye Cente

Chandler, Arizona, United States

Site Status

Fishkind, Bakewell & Maltzman Eye Care & Surgery Cente

Tucson, Arizona, United States

Site Status

Boozman-Hof Regional Eye Clinic

Rogers, Arkansas, United States

Site Status

Empire Eye & Laser Center

Bakersfield, California, United States

Site Status

Atlantis Eye Care

Huntington Beach, California, United States

Site Status

Scripps Clinic Medical Group

La Jolla, California, United States

Site Status

Southern California Eye Physicians & Associates

Long Beach, California, United States

Site Status

Feinerman Vision Center

Newport Beach, California, United States

Site Status

Coastal Vision

Orange, California, United States

Site Status

California Eye Medical Specialists

Pasadena, California, United States

Site Status

Wolstan & Goldberg Eye Associates

Torrance, California, United States

Site Status

Florida Eye Microsurgical Institute, Inc.

Boynton Beach, Florida, United States

Site Status

Katzen Eye Care & Laser Center

Boynton Beach, Florida, United States

Site Status

The Eye Associates

Bradenton, Florida, United States

Site Status

Cape Coral Eye Center

Cape Coral, Florida, United States

Site Status

Levenson Eye Associates, Inc.

Jacksonville, Florida, United States

Site Status

Northwestern University Feinberg School of Medicine

Chicago, Illinois, United States

Site Status

Virdi Eye Clinic & Laser Vision Center

Rock Island, Illinois, United States

Site Status

Senior Health Services

Louisville, Kentucky, United States

Site Status

Chesapeake Eye Care and Laser Center

Annapolis, Maryland, United States

Site Status

Solomon Eye Associates

Bowie, Maryland, United States

Site Status

Eye Doctors of Washington

Chevy Chase, Maryland, United States

Site Status

Oakland Ophthalmic Surgery, P.C.

Birmingham, Michigan, United States

Site Status

TLC Eye Care and Laser Centers

Chelsea, Michigan, United States

Site Status

Mercy Clinic Eye Specialist

Springfield, Missouri, United States

Site Status

Ophthalmology Associates

St Louis, Missouri, United States

Site Status

Ophthalmology Consultants

St Louis, Missouri, United States

Site Status

Kindermann Eye Associates

Cherry Hill, New Jersey, United States

Site Status

Matossian Eye Associates

Pennington, New Jersey, United States

Site Status

Eye Associates of New Mexico

Albuquerque, New Mexico, United States

Site Status

Pamel Vision & Laser Group

New York, New York, United States

Site Status

Fine, Hoffman & Sims

Eugene, Oregon, United States

Site Status

The Eye Center of Central PA

Allenwood, Pennsylvania, United States

Site Status

Ludwick Eye Center

Chambersburg, Pennsylvania, United States

Site Status

Scott & Christie and Associates, PC

Cranberry Township, Pennsylvania, United States

Site Status

Carolina Cataract & Laser Center

Ladson, South Carolina, United States

Site Status

Vance Thompson Vision

Sioux Falls, South Dakota, United States

Site Status

Loden Vision Centers

Goodlettsville, Tennessee, United States

Site Status

Houston Eye Associates

Houston, Texas, United States

Site Status

Whitsett Vision Group

Houston, Texas, United States

Site Status

Focal Point Vision

San Antonio, Texas, United States

Site Status

San Antonio Eye Specialists

San Antonio, Texas, United States

Site Status

Clarus Eye Centre

Lacey, Washington, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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TIOL-202-TPAS

Identifier Type: -

Identifier Source: org_study_id

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