Bone Microarchitecture in Women Practicing Golf

NCT ID: NCT02544399

Last Updated: 2015-09-09

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 67 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2009-11-30
• Study Completion Date: 2013-06-30

Brief Summary

After the age of 50, one in three women and one in eight men will experience at least one fragility fracture during the rest of their lives. It is currently recognized that physical activity has an osteogenic actions, especially when it includes the impact transmitted to the skeleton. In this context, the investigators propose a study to determine whether the regular practice of golf could be particularly beneficial for the skeleton, not only in the lower limbs, due to repeated impacts to the ground when it requires sustained walking, but also the upper limbs due to the impacts transmitted by the club at the time of striking the ball, as has been amply demonstrated with racquet sports.

Detailed Description

Each patient will have 1 blood samples and 1 measure of bone by 3D micro-tomography (3D CT Scan).These examinations and sampling will take place on 1 day.

Conditions

Bone Microarchitecture

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Subject practicing golf and accept bone measure

Each patient will have 1 blood sample and 1 measure of bone by 3D micro-tomography

3D CT scan

Intervention Type: OTHER

Measure of bone micro-architecture by 3D micro-tomography

Subject practicing foot walk and accept bone measure

Each patient will have 1 blood sample and 1 measure of bone by 3D micro-tomography

3D CT scan

Intervention Type: OTHER

Measure of bone micro-architecture by 3D micro-tomography

Subject sedentary and accept bone measure

Each patient will have 1 blood sample and 1 measure of bone by 3D micro-tomography

3D CT scan

Intervention Type: OTHER

Measure of bone micro-architecture by 3D micro-tomography

Interventions

3D CT scan

Measure of bone micro-architecture by 3D micro-tomography

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Golfers: Regular playing golf for over 2 years at 8 to 12 hours per week recruited into golf clubs.
• Walkers: regular practice of walking for over 2 years at 8 to 12 hours per week recruited into the walking clubs.
• Sedentary: no intensive physical activity (<2 hours / week), recruited in clubs seniors.

Exclusion Criteria

• concomitant bone disease ,
• Hip prosthesis the dominant side
• Endocrinopathy
• hypercalcemia, vitamin D deficiency, hypo- or hyper calciuria
• Active smoking (more than 5 cigarettes / day), chronic alcoholism,
• Treatments received in the previous six months and resounding on bone metabolism such growth promoters, all osteoporosis, corticosteroids.

• Minimum Eligible Age: 60 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: Yes

Sponsors

Centre Hospitalier Universitaire de Saint Etienne

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Thierry THOMAS, MD-PhD

Role: PRINCIPAL_INVESTIGATOR

CHU SAINT-ETIENNE

Other Identifiers

2008-A01265-50

Identifier Type: OTHER

Identifier Source: secondary_id

0801092

Identifier Type: -

Identifier Source: org_study_id