The Effect of Altered Gravity Condition on Postural Control

NCT ID: NCT02517229

Last Updated: 2015-08-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

18 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-09-30

Brief Summary

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The scientific goal of this experiment is to evaluate changes in balance control in response to microgravity during reactive balance tasks. For that purpose, kinematic and neuromuscular parameters under microgravity are compared to normal gravity conditions. To induce postural responses among the test subjects, an electromagnetic maneuverable postural platform will be used in order to randomly elicit perturbations. Postural reactions will be quantified by means of mechanical and electromyographic data. In Addition, peripheral nerve stimulation will be used to assess the spinal excitability by means of H-reflex recordings. H-reflex measurements were chosen as they allow reliable information about inhibitory and facilitatory mechanisms taking place at the spinal level.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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in balance control in response to microgravity

to evaluate changes in balance control in response to microgravity during reactive balance tasks compared to normal gravity.

Group Type OTHER

Parabolic flight

Intervention Type OTHER

balance control measurements

Intervention Type OTHER

electromagnetic maneuverable postural platform

Intervention Type DEVICE

Interventions

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Parabolic flight

Intervention Type OTHER

balance control measurements

Intervention Type OTHER

electromagnetic maneuverable postural platform

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Healthy volunteers (men or women)
* Aged from 21 to 65
* Affiliated to a Social Security system and, for non-French resident, holding a European Health Insurance Card (EHIC)
* Who accepted to take part in the study
* Who have given their written stated consent
* Who has passed a medical examination similar to a standard aviation medical examination for private pilot aptitude. There will be no additional test performed for subject selection.

Exclusion Criteria

* Person who took part in a previous biomedical research protocol, of which exclusion period is not terminated
* Person with medical history of neurological disorders
* Person with medical history of musculoskeletal disorders of the lower limbs, especially of the ankle and knee joint.
* Pregnant women
Minimum Eligible Age

21 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Caen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Umr Ucbn/Inserm U1075 Comete

Caen, Basse-Normandie, France

Site Status RECRUITING

Countries

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France

Facility Contacts

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Pierre Denise, MD PhD

Role: primary

332068214

Other Identifiers

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12-084

Identifier Type: -

Identifier Source: org_study_id

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