Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
540 participants
INTERVENTIONAL
2016-05-31
2020-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
OTHER
NONE
Study Groups
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Friends for Life Circles (FLC)
The intervention will include formation of peer support groups of eight to ten women in the community with incorporation of income generating activities to improve maternal adherence to clinic appointments and life long antiretroviral therapy
Friends for Life Circles (FLCs).
The intervention 'Friends for Life Circles" (FLCs) will build dynamic peer group support in the community aimed at supporting maternal adherence to appointment keeping and taking lifetime antiretroviral drugs
Standard of Care (SOC)
Normal standard of care and follow up. The standard care provided in the clinic will be provided for the control arem
No interventions assigned to this group
Interventions
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Friends for Life Circles (FLCs).
The intervention 'Friends for Life Circles" (FLCs) will build dynamic peer group support in the community aimed at supporting maternal adherence to appointment keeping and taking lifetime antiretroviral drugs
Eligibility Criteria
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Inclusion Criteria
* Documentation of pregnancy through clinical assessment or pregnancy test
* Documentation of confirmed HIV-positive sero-status at the time of screening
* Accepting to receive option B+ for PMTCT
* Providing written informed consent to participate in the randomized trial.
* Agreeing to come the study clinic for scheduled appointments
* Agreeing to be home visited as needed to ensure follow up
* Residing within a 20 km radius around the study clinic
* Not planning to move out of the catchment area within the next 2 years
Exclusion Criteria
18 Years
55 Years
FEMALE
No
Sponsors
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Johns Hopkins University
OTHER
MU-JHU CARE
OTHER
Responsible Party
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Philippa Musoke, MBChB, PhD
Site Leader
Principal Investigators
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Philippa Musoke, MD PhD
Role: PRINCIPAL_INVESTIGATOR
MU-JHU CARE
Locations
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MUJHU Research Collaboration
Kampala, , Uganda
Countries
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References
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Amone A, Gabagaya G, Wavamunno P, Rukundo G, Namale-Matovu J, Malamba SS, Lubega I, Homsy J, King R, Nakabiito C, Namukwaya Z, Fowler MG, Musoke P. Enhanced peer-group strategies to support the prevention of mother-to-child HIV transmission leads to increased retention in care in Uganda: A randomized controlled trial. PLoS One. 2024 Apr 19;19(4):e0297652. doi: 10.1371/journal.pone.0297652. eCollection 2024.
Gabagaya G, Rukundo G, Amone A, Wavamunno P, Namale-Matovu J, Lubega I, Nakabiito C, Namukwaya Z, Nolan M, Malamba SS, King R, Homsy J, Fowler MG, Musoke P. Prevalence of undetectable and suppressed viral load in HIV-infected pregnant women initiating Option B+ in Uganda: an observational study nested within a randomized controlled trial. BMC Infect Dis. 2021 Sep 4;21(1):907. doi: 10.1186/s12879-021-06608-4.
Other Identifiers
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Musoke-R01-080476-Option B+
Identifier Type: -
Identifier Source: org_study_id
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