Pilot Mammography Reader Study to Assess Breast Cancer Detection in FFDM Plus DBT Versus FFDM Alone

NCT ID: NCT02511730

Last Updated: 2023-09-21

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-06-30

Study Completion Date

2015-08-31

Brief Summary

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The purpose of this pilot is to provide credible performance estimate information in order to conduct subsequent reader studies.

Detailed Description

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This pilot reader study was to determine the following:

1. the radiologist's performance metrics for the two reading modalities, i.e., "FFDM read on the Aspire Bellus workstation" and "FFDM read in conjunction with DBT read on the Aspire Bellus workstation",;
2. the magnitude and direction of differences between performance metrics for the two modalities; and
3. variance components and correlations that would influence samples sizes and case mix for the subsequent pivotal reader study comparing performance metrics between the two modalities.

Conditions

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Breast Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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FFDM Plus DBT

Breast Images with FFDM and DBT

Group Type EXPERIMENTAL

FFDM Plus DBT

Intervention Type DEVICE

FujiFilm Aspire Cristalle System

FFDM Alone

Breast Images with FFDM alone

Group Type ACTIVE_COMPARATOR

FFDM

Intervention Type DEVICE

FujiFilm Aspire Cristalle System

Interventions

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FFDM Plus DBT

FujiFilm Aspire Cristalle System

Intervention Type DEVICE

FFDM

FujiFilm Aspire Cristalle System

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Female subjects participating in FMSU004A protocol with known clinical status

Exclusion Criteria

* Subjects with unknown clinical status not participating in FMSU004A protocol.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Fujifilm Medical Systems USA, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Robert M Uzenoff

Role: STUDY_DIRECTOR

Fujifilm Medical Systems USA, Inc.

Locations

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Scottsdale Medical Imaging, Limited (SMIL)

Scottsdale, Arizona, United States

Site Status

Elizabeth Wende Breast Care, LLC (EWBC)

Rochester, New York, United States

Site Status

University of North Carolina - at Chapel Hill

Chapel Hill, North Carolina, United States

Site Status

University of Texas Health Science Center at San Antonio

San Antonio, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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FMSU2013-004E

Identifier Type: -

Identifier Source: org_study_id

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