Monocentric Study on Acetabulum Patient-specific Pin Drilling Guides

NCT ID: NCT02499523

Last Updated: 2017-03-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

7 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-06-16

Study Completion Date

2016-10-21

Brief Summary

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A prospective, interventional, monocentric, controlled and randomized study will compare a conventional surgical technique to a surgical technique with the assistance of the Acetabular Cup Orientation Guide (ACOG, Materialise) System during total hip replacement (THR).

Detailed Description

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Background: The Acetabular Cup Orientation Guide(ACOG) System from MATERIALISE NV was developed and is intended to be used as a surgical instrument to assist in the positioning of acetabular cup components intra-operatively using anatomical landmarks of the pelvis that are clearly identifiable on preoperative computed tomography (CT) imaging scans.

Use of ACOG is a relative new technique. ACOG, based on CT imaging data, fit directly into the patient's anatomy and enable primary total hip replacement . Data showing extra benefit of this technique compared to conventional THR technique are not widely available.

Aim: To determine the safety of this new surgical technique compared to conventional THR.

Methods: 30 participants will be randomized to 2 groups. One group will be operated for a THR with the conventional technique and the other group will be operated for a THR with the assistance of the ACOG System. CT imaging will be taken pre and post operatively to measure cup orientation.

Conditions

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Osteoarthritis, Hip

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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THR with conventional technique

Use of conventional technique in THR

Group Type ACTIVE_COMPARATOR

THR with conventional technique

Intervention Type PROCEDURE

THR with conventional technique.

THR with ACOG

THR with Acetabular Cup Orientation Guides (ACOG)

Group Type EXPERIMENTAL

THR with Acetabular Cup Orientation Guides (ACOG)

Intervention Type PROCEDURE

THR with the ACOG System.

Interventions

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THR with conventional technique

THR with conventional technique.

Intervention Type PROCEDURE

THR with Acetabular Cup Orientation Guides (ACOG)

THR with the ACOG System.

Intervention Type PROCEDURE

Other Intervention Names

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ACOG, Materialise

Eligibility Criteria

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Inclusion Criteria

* Is selected to undergo a primary THR
* Informed consent

Exclusion Criteria

* Is unable to undergo CT imaging of the full pelvis
* Requires surgical treatment within less than 4 weeks of initiation
* Is unable to undergo a THR through a anterolateral approach
* Presents acute/chronic local or systemic infection
* Is allergic to polyamide
* Patient's BMI \> 35
* Patients with severe wear of the acetabular rim or other disorders that affect acetabular rim anatomy and bony landmark recognition.Patients exhibiting severe wear.
* Has impaired decision-making capacity
* Is a prisoner
* Is pregnant
* Has metal components that will result in scatter on the CT imaging
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Materialise

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pieter Dolhain

Role: PRINCIPAL_INVESTIGATOR

AZ Monica

Locations

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AZ Monica

Antwerp, , Belgium

Site Status

Countries

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Belgium

References

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Hananouchi T, Saito M, Koyama T, Hagio K, Murase T, Sugano N, Yoshikawa H. Tailor-made surgical guide based on rapid prototyping technique for cup insertion in total hip arthroplasty. Int J Med Robot. 2009 Jun;5(2):164-9. doi: 10.1002/rcs.243.

Reference Type RESULT
PMID: 19248055 (View on PubMed)

Hananouchi T, Saito M, Koyama T, Sugano N, Yoshikawa H. Tailor-made Surgical Guide Reduces Incidence of Outliers of Cup Placement. Clin Orthop Relat Res. 2010 Apr;468(4):1088-95. doi: 10.1007/s11999-009-0994-4. Epub 2009 Jul 24.

Reference Type RESULT
PMID: 19629605 (View on PubMed)

Other Identifiers

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SMAT003

Identifier Type: -

Identifier Source: org_study_id

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