Neurogenic Dysphonia/Dysphagia Registry

NCT ID: NCT02493491

Last Updated: 2016-09-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

146 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-06-30

Study Completion Date

2016-09-30

Brief Summary

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The Neurogenic Dysphonia/Dysphagia Registry is designed to be purely observational (i.e. non-interventional, exploratory). Patient data collected from the registry is expected to be consistent with any information which can be obtained during usual care of patients with dysphonia/dysphagia treated with vocal fold augmentation.

Detailed Description

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The Neurogenic Dysphonia/Dysphagia Registry is a 510K post-clearance multicenter, observational, open-label registry of the benefits and risks of management and outcomes of patients with neurogenic dysphonia/dysphagia who have received vocal fold augmentation (VFA).

Enrollment is open to all eligible patients meeting all of the inclusion and none of the exclusion criteria, with a target of 400 patients. Up to 100 sites in the US and abroad will be a part of the registry. Sites will provide retrospective data for active patients who have undergone VFA within the past 24 months at the site and also begin to prospectively enroll patients who are receiving VFA as a part of their usual care. Patients will be followed for up to five years prospectively, until lost to follow-up, or death.

Conditions

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Neurogenic Dysphonia Neurogenic Dysphagia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Males and Females, ≥18 years of age
* Diagnosis of neurogenic dysphonia/dysphagia
* Under active treatment with VFA and follow-up care

Exclusion Criteria

• Patients with:

* Vocal fold scar
* Laryngeal cancer defect
* Irradiation to the larynx
* Laryngeal trauma
* End-stage cancer
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Carelon Research

OTHER

Sponsor Role collaborator

Cmed Clinical Services

OTHER

Sponsor Role collaborator

Merz North America, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Scott Sykes, MD

Role: STUDY_DIRECTOR

Merz North America, Inc.

Locations

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Merz Clinical Site

La Jolla, California, United States

Site Status

Merz Clinical Site

Sacramento, California, United States

Site Status

Merz Clinical Site

Augusta, Georgia, United States

Site Status

Merz Clinical Site

Boston, Massachusetts, United States

Site Status

Merz Clinical Site

Burlington, Massachusetts, United States

Site Status

Merz Clinical Site 0010334

New York, New York, United States

Site Status

Merz Clinical Site 0010068

New York, New York, United States

Site Status

Merz Clinical Site 0010333

Sleepy Hollow, New York, United States

Site Status

Merz Clinical Site

Durham, North Carolina, United States

Site Status

Merz Clinical Site 0010332

Pittsburgh, Pennsylvania, United States

Site Status

Merz Clinical Site

Houston, Texas, United States

Site Status

Merz Clinical Site

Norfolk, Virginia, United States

Site Status

Countries

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United States

Other Identifiers

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METIS M930901001; WI P150999

Identifier Type: -

Identifier Source: org_study_id

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