A Clinical Study of the CardiAQ™ TMVI System (Transapical DS)

NCT ID: NCT02478008

Last Updated: 2016-03-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

2 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-06-30

Study Completion Date

2015-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of the study is to evaluate the initial short and long-term safety and performance of the CardiAQ™ Transcatheter Mitral Valve Implantation System using the Transapical Delivery System.

The study will enroll patients with moderate to severe mitral valve regurgitation who are considered high or extreme risk for mortality and morbidity from conventional open heart surgery.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Mitral Insufficiency Heart Valve Disease Cardiovascular Disease Heart Disease

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Transcatheter Mitral Valve Replacement Mitral Regurgitation Mitral Insufficiency Transapical

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

CardiAQ TMVI System (Transapical DS)

Group Type EXPERIMENTAL

CardiAQ TMVI System (Transapical DS)

Intervention Type DEVICE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

CardiAQ TMVI System (Transapical DS)

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* NYHA Classification ≥ III
* Left Ventricular Ejection Fraction ≥ 30%
* Mitral regurgitation ≥ Grade 3+
* Subject meets anatomical eligibility criteria for the investigational device
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Edwards Lifesciences

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Lars Søndergaard, MD, DMSc

Role: PRINCIPAL_INVESTIGATOR

Rigshospitalet University Hospital (Copenhagen, Denmark)

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Rigshospitalet University Hospital

Copenhagen, , Denmark

Site Status

Centre hospitalier régional universitaire de Lille

Lille, , France

Site Status

Hôpital Européen Georges-Pompidou

Paris, , France

Site Status

Centre Hospitalier Universiatier de Toulouse

Toulouse, , France

Site Status

Medisch Centrum Leeuwarden

Leeuwarden, , Netherlands

Site Status

St. Antonius Ziekenhuis

Nieuwegein, , Netherlands

Site Status

Erasmus University Medical Center

Rotterdam, , Netherlands

Site Status

Leeds General Infirmary

Leeds, , United Kingdom

Site Status

New Cross Hospital Heart Center

Wolverhampton, , United Kingdom

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Denmark France Netherlands United Kingdom

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

CIP-3102-01

Identifier Type: -

Identifier Source: org_study_id