PD-Improved Dialysis Efficiency With Adapted APD

NCT ID: NCT02470598

Last Updated: 2020-08-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

182 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-03-31

Study Completion Date

2020-06-30

Brief Summary

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The aim of this study is to observe the effect of adapted APD (aAPD) on maintenance and/or improvement of the hydration status of more than 250 PD patients, and to observe the tolerability of the therapy over a long period.

Detailed Description

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In some studies it has been observed that the use of a combination of short dwell/small volume and long dwell/large volume can improve the effectiveness of APD. However, these studies have been performed in a small number of patients during a short observation period.

The aim of this study is to assess the hydration status of PD patients treated with aAPD and observe its development during one year using the BCM-Body Composition Monitor (BCM), a bioimpedance spectroscopy (BIS) device. In addition, it is intended to observe the variability of aAPD prescriptions and their influence on the hydration status of the patients.

This is a purely non-interventional, observational study, where treatment decisions are completely guided by the discretion of the attending nephrologists.

Conditions

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Chronic Renal Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Treatment with Adapted Automated Peritoneal Dialysis (aAPD)

This is a purely non-interventional, observational study, where treatment decisions are completely guided by the discretion of the attending nephrologists

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* CKD patients with indication for renal replacement therapy
* Patient treated or to be treated with aAPD
* Fluid status regularly monitored with BCM

Exclusion Criteria

* Patients who have any condition prohibiting the use of BCM like patients with major amputations (e.g. lower leg)
* Participation in an interventional study which could have an effect on the study objectives hydration status and dialysis adequacy (e.g. studies on PD solutions, studies on diuretics)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fresenius Medical Care Deutschland GmbH

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michel Fischbach, Prof.

Role: STUDY_DIRECTOR

University Hospital Hautepierre

Manel Vera, Dr.

Role: STUDY_DIRECTOR

Hospital Clinic i Provinvial de Barcelona

Emilio Galli, Dr.

Role: STUDY_DIRECTOR

Ospedale "Treviglio-Caravaggio" di Treviglio

Cecile Courivaud, Dr.

Role: STUDY_DIRECTOR

University Hospotal Besancon

Virpi Rauta, Dr.

Role: STUDY_DIRECTOR

Helsinki Univerity Hospital

Locations

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Faculty Hospital Brno-Bohunice

Brno, , Czechia

Site Status

Hospital Liberec

Liberec, , Czechia

Site Status

Regional Hospital in Mlada Boleslav

Mladá Boleslav, , Czechia

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Hospital Nove Mesto na Morave

Nové Město na Moravě, , Czechia

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Faculty Hospital Pilsen

Pilsen, , Czechia

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Faculty Hospital Karlovo namesti

Prague, , Czechia

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Faculty Hospital Strahov

Prague, , Czechia

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NC centre Vinohrady

Prague, , Czechia

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NC centre Sokolov

Sokolov, , Czechia

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Hospital Trebic

Třebíč, , Czechia

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Regional Hospital Viborg

Viborg, , Denmark

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Helsinki University Hospital

Helsinki, , Finland

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Kymenlaakso Central Hospital

Kotka, , Finland

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Regional Hospital Roskilde

Lappeenranta, , Finland

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Hospital Selayang

Batu Caves, , Malaysia

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Gleneagles Hospital Kuala Lumpur (GHKL)

Kuala Lumpur, , Malaysia

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Hospital Universiti Kebangsaan Malaysia (HUKM)

Kuala Lumpur, , Malaysia

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Hospital Serdang

Serdang, , Malaysia

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Hospital Seremban

Seremban, , Malaysia

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Complejo Hospitalario universitario de Albacete

Albacete, , Spain

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Fundación Hospital de Alcorcón

Alcorcón, , Spain

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Complejo Asistencial de Avila

Ávila, , Spain

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Fundacion Puigvert

Barcelona, , Spain

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Hospital Clinic de Barcelona

Barcelona, , Spain

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Hospital de Basurto

Bilbao, , Spain

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Hospital General de Castellón

Castellon, , Spain

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Hospital Universitario di Girona Josep Trueta

Girona, , Spain

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Hospital General Virgen de las Nieves

Granada, , Spain

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Complejo hospitalario de Jaén

Jaén, , Spain

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Complejo Hospitalario San Millán-San Pedro De La Rioja

Logroño, , Spain

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Hospital Universitario Lucus Agusti

Lugo, , Spain

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Hospital Clínico San Carlos

Madrid, , Spain

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Hospital Universitario Ramón y Cajal

Madrid, , Spain

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Hospital Universitario Puerta de Hierro

Majadahonda, , Spain

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Hospital Carlos Haya

Málaga, , Spain

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Complexo Hospitalario Universitario de Ourense (CHUO)

Ourense, , Spain

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Hospital Universitario Central de Asturias (HUCA)

Oviedo, , Spain

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Hospital Universitatio Donostia

San Sebastián, , Spain

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Complejo Hospital Universitario de Santiago (CHUS)

Santiago de Compostela, , Spain

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Hospital Clínico de Valencia

Valencia, , Spain

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Hospital Peset

Valencia, , Spain

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Hospital Universitari i Politècnic La Fe

Valencia, , Spain

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Hospital Txagorritxu

Vitoria-Gasteiz, , Spain

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Danderyds Sjukhus AB

Danderyd, , Sweden

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Höglandssjukhuset Eksjö/Nässjö

Eksjö, , Sweden

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Kalmar Hospital

Kalmar, , Sweden

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Skåne University Hospital

Lund, , Sweden

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Länssjukhuset Sundsvall

Sundsvall, , Sweden

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Norra Älvsborgs Länssjukhus

Trollhättan, , Sweden

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Norrlands University Hopsital

Umeå, , Sweden

Site Status

Countries

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Czechia Denmark Finland Malaysia Spain Sweden

Other Identifiers

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PD-aAPD-01-INT

Identifier Type: -

Identifier Source: org_study_id

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