Tai Chi for Enhancing Motor and Cognitive Function in Parkinson's Disease

NCT ID: NCT02418780

Last Updated: 2016-08-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-05-31

Study Completion Date

2016-04-30

Brief Summary

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The purpose of this feasibility study is to preliminarily evaluate the effects of Tai Chi - a mind-body exercise - on motor and cognitive function as well as quality of life in individuals recently diagnosed with Parkinson's disease (PD).

Detailed Description

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Specific Aim 1: To assess the feasibility of recruiting and retaining individuals with PD into a 6-month randomized controlled trial of Tai Chi exercise.

Specific Aim 2: To collect preliminary data on the efficacy of Tai Chi on improving gait and balance dynamics, physical and cognitive function, exercise activity, self-efficacy, mood, and quality of life in individuals with PD.

Conditions

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Parkinson Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Tai Chi

6-month Tai Chi training program combined with usual medical care

Group Type EXPERIMENTAL

Tai Chi

Intervention Type OTHER

6-month Tai Chi exercise program meeting 2 times per week plus DVD for home practice

Usual Care

Waitlist control group receiving usual medical care alone

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Tai Chi

6-month Tai Chi exercise program meeting 2 times per week plus DVD for home practice

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Individuals recently diagnosed with idiopathic PD (≤ 10 years)
* Limited disease progression
* If taking PD-related medication, willingness to undergo baseline and follow-up testing while off medication
* Willingness to commit to the study protocols and complete Tai Chi program
* Willingness to be videotaped and audio-recorded during testing

Exclusion Criteria

* Diagnosis of any form of atypical parkinsonism
* History of: stroke, head trauma, brain tumor, brain injury, seizures or other central nervous system condition, orthopedic impairment or other disease that could likely contribute to a gait disturbance or parkinsonism
* Any severe, chronic condition or acute medical event for which participation in exercise programs is contraindicated (e.g. debilitating Rheumatoid Arthritis, history of frequent falls, unhealed fracture)\*\*

\*\* Unless the participant is able to obtain formal written approval from his/her treating physician granting permission to participate in our Tai Chi exercise program
* Participation in brain stimulation within the past 3 months
* Family history of seizures or unexplained loss of consciousness
* Current history of dementia or severe psychiatric illness. Patients with mild (non-suicidal) depression and/or anxiety may be included
* Acute illness requiring hospitalization within past 3 months
* History of deep brain stimulation or other brain surgery
* Participation in brain stimulation within the past 3 months
* Regular use of walking aid
* Significant Tai Chi experience (\> 6 months training in past 2 years)
Minimum Eligible Age

40 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Spaulding Rehabilitation Hospital

OTHER

Sponsor Role collaborator

Beth Israel Deaconess Medical Center

OTHER

Sponsor Role collaborator

Harvard University Faculty of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Peter Wayne

Assistant Professor of Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Peter M Wayne, PhD

Role: PRINCIPAL_INVESTIGATOR

Harvard University Faculty of Medicine

Locations

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Brigham and Women's Hospital

Boston, Massachusetts, United States

Site Status

Countries

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United States

References

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Ernst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2024 Apr 8;4(4):CD013856. doi: 10.1002/14651858.CD013856.pub3.

Reference Type DERIVED
PMID: 38588457 (View on PubMed)

Ernst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2023 Jan 5;1(1):CD013856. doi: 10.1002/14651858.CD013856.pub2.

Reference Type DERIVED
PMID: 36602886 (View on PubMed)

Other Identifiers

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2013P002343

Identifier Type: -

Identifier Source: org_study_id

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