Impact of Aerobic Training and Combined in Inflammatory Markers in Patients With Adolescent Idiopathic Scoliosis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-09-30

Study Completion Date

2016-03-31

Brief Summary

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Inflammatory markers have been analyzed in several diseases of unknown etiology, in the expectation of increasing therapeutic perspectives. This possibility arises from the different levels of tissue injury with low-grade chronic inflammation that have been observed in studies in which the markers were not evaluated traditionally, and today have influenced clinical management.

The investigators aimed, therefore, to evaluate the inflammatory markers in patients with AIS before and after aerobic and combined exercise training.

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Detailed Description

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Inflammatory markers have not been evaluated in adolescent idiopathic scoliosis (AIS), but this deformity potentially involves various musculoskeletal structures permanently, which justifies the analysis. A low-grade chronic inflammation may be related to the lower capacity in exercise performance observed in this population, which must be stimulated to perform standardized physical activity.

Conditions

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Scoliosis Adolescent Scoliosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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combined group (treadmill and resisted)

\- 10 minutes of warming, aerobic training 40 minutes on a treadmill (60-80% of maximum heart rate) and resisted training in equipment and free weights for 10 minutes with a set of 10 repetitions in quadriceps, triceps and biceps of the arms and legs (36 sessions)

Group Type EXPERIMENTAL

combined exercise

Intervention Type OTHER

aerobic training 40 minutes on a treadmill (60-80% of maximum heart rate); resisted training in equipment and free weights for 10 minutes with a set of 10 repetitions in quadriceps, triceps and biceps of the arms and legs

treadmill

Intervention Type DEVICE

aerobic group (treadmill)

10 minutes of warming, aerobic training 40 minutes on a treadmill (60-80% of maximum heart rate) for 36 sessions

Group Type ACTIVE_COMPARATOR

aerobic exercise

Intervention Type OTHER

aerobic training 40 minutes on a treadmill (60-80% of maximum heart rate)

treadmill

Intervention Type DEVICE

Interventions

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aerobic exercise

aerobic training 40 minutes on a treadmill (60-80% of maximum heart rate)

Intervention Type OTHER

combined exercise

aerobic training 40 minutes on a treadmill (60-80% of maximum heart rate); resisted training in equipment and free weights for 10 minutes with a set of 10 repetitions in quadriceps, triceps and biceps of the arms and legs

Intervention Type OTHER

treadmill

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* thoracic curvature ≥ 45 degrees
* indication for surgical treatment of spinal deformity
* absence of pulmonary, cardiac, articular or neurological disorder, atopic dermatitis and previous or current allergy
* agree part in the research with a assent statement and the person responsible with the consent form and informed

Exclusion Criteria

* acknowledged chronic liver or kidney inflammatory disease
* use of corticosteroids, acetylsalicylic acid or other nonhormonal anti-inflammatory clinical or laboratorial evidence of infection
* severe obesity

Minimum Eligible Age

10 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No