APPLICATION OF MOLECULAR TECHNIQUES FOR IMPROVING THE DIAGNOSIS AND TREATMENT OF NODULAR THYROID LESIONS.
NCT ID: NCT02323724
Last Updated: 2016-09-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
25 participants
OBSERVATIONAL
2015-02-28
2015-07-31
Brief Summary
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Detailed Description
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Design: Retrospective observational study. Scope: The study will be peformed at the Pathology Service, from cytological samples and paraffin file post-diagnosis. Mutations are detected by pyrosequencing technique.
Subject of study:
Cases with histological diagnosis of papillary carcinoma (CP) and previous cytological diagnosis in groups III, IV and V Bethesda, collected between October 1989 and July 2014 in Corporació Parc Taulí.
Methodology:
* Identification of cases
* Detection of BRAF V600E mutation, initially in histological material from the surgical specimen, and if present, detection in cytological material.
The statistical analysis will use SPSS. Univariate and bivariate analysis will be done. Results will be presented in the form of frequency tables and percentages for qualitative variables and by average, median and standard deviation for quantitative variables. Pearson chi-square or Fisher's exact test will be applied. The Student t test or the Mann-Whitney test will be performed for quantitative variables.
Conditions
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Study Design
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CASE_ONLY
RETROSPECTIVE
Study Groups
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Selected Papillary carcinoma
Cases with histological diagnosis of papillary carcinoma (CP) and previous cytological diagnosis in groups III, IV and V Bethesda, collected between October 1989 and July 2014 in Corporació Parc Taulí.
BRAF V600E mutation by pyrosequencing technique
Interventions
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BRAF V600E mutation by pyrosequencing technique
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
ALL
No
Sponsors
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Corporacion Parc Tauli
OTHER
Responsible Party
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Rosa Bella Cueto
Coordinator of Pathology
Locations
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Corporació Sanitària Parc Taulí
Sabadell, Barcelona, Spain
Countries
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Other Identifiers
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2014/617
Identifier Type: -
Identifier Source: org_study_id
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