Safety and Performance Study of the Nyxoah SAT System for Treating OSA

NCT ID: NCT02312479

Last Updated: 2016-09-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

6 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-12-31

Study Completion Date

2016-04-30

Brief Summary

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A prospective open-label, single treatment study to assess the safety and the performance of the Nyxoah SAT system for the treatment of Obstructive Sleep Apnea

Detailed Description

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Conditions

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Obstructive Sleep Apnea

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Nyxoah SAT therapy

Group Type EXPERIMENTAL

Nyxoah SAT system

Intervention Type DEVICE

The Nyxoah SAT system is comprised of an implantable nerve stimulator implanted over one of the tongue muscles via a minimally invasive procedure. Stimulation of the Hypoglossal nerves causes the tongue muscles to contract, thus maintaining an open airway during sleep.

Interventions

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Nyxoah SAT system

The Nyxoah SAT system is comprised of an implantable nerve stimulator implanted over one of the tongue muscles via a minimally invasive procedure. Stimulation of the Hypoglossal nerves causes the tongue muscles to contract, thus maintaining an open airway during sleep.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Diagnosed with moderate to severe Obstructive Sleep Apnea
* Have failed or have not tolerated CPAP treatment
* Willing and capable of providing informed consent
* Willing and capable of returning to all follow-up visits and sleep studies, including evaluation procedures and filling out questionnaires

Exclusion Criteria

* BMI limits
* Subjects with complete concentric collapse at the soft palate level per endoscopy
Minimum Eligible Age

21 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Nyxoah S.A.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Joachim T Maurer, OA Dr. med.

Role: PRINCIPAL_INVESTIGATOR

Universitäts-HNO-Klinik Mannheim

Evert Hamans, PhD Dr.

Role: PRINCIPAL_INVESTIGATOR

Universiteit Antwerpen

Locations

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Antwerp University Hospital

Edegem, , Belgium

Site Status

Universitäts-HNO-Klinik Mannheim

Mannheim, , Germany

Site Status

Countries

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Belgium Germany

Other Identifiers

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SAT2014A

Identifier Type: -

Identifier Source: org_study_id

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