Transthoracic Echocardiographic Evaluation of the Cardiac Function During Transurethral Resection of Prostate in Elderly Patients

NCT ID: NCT02288780

Last Updated: 2019-03-18

Basic Information

• Recruitment Status: TERMINATED
• Total Enrollment: 2 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2014-12-31
• Study Completion Date: 2015-05-01

Brief Summary

Transurethral resection of the prostate (TURP) is a standard surgical treatment for benign prostatic hyperplasia (BPH). Non-conductive irrigation fluid is used to maintain good visibility of the operating field during resection of the prostate. Absorption of this hypotonic solution into the bloodstream can cause fluid overload and dilutional hyponatremia, resulting in adverse cardiovascular and central nervous system effects, transurethral resection (TUR) syndrome. BPH is common in elderly men above 60 years old. These aged people commonly have diastolic impairment by normal physiologic change without consistent symptom. This study aimed to evaluate the cardiac function focused mainly diastolic function during TURP with transthoracic echocardiography. Also, we will focus the effets of amount of irrgation fluid on left ventricular diastolic function in patients with pre-existing diastolic dysfunction.

Conditions

BPH

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Control

BPH patients with normal diastolic function

No interventions assigned to this group

Diastolic dysfunction

BPH patients with preoperative diastolic dysfunction

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

1. Above 65years of age

2. American Society of Anesthesiologists (ASA) Physical Status I, II, III.

3. undergoing transurethral resection of the prostate(TURP)"

Exclusion Criteria

1. severe coagulopathy or bleeding disorder(platelet count<75000, PT INR >1.2)

2. short stature (under 150 cm)

3. underwent coronary artery bypass graft

4. contraindications of regional anesthesia "

• Minimum Eligible Age: 65 Years
• Maximum Eligible Age: 85 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: No

Sponsors

Yonsei University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Other Identifiers

4-2014-0734

Identifier Type: -

Identifier Source: org_study_id