The Robot-Assisted Laparoscopic Radical Prostatectomy Combined Anterior and Posterior Approach

NCT ID: NCT06020287

Last Updated: 2023-08-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

233 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-01

Study Completion Date

2022-12-27

Brief Summary

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The goal of this observational study was to compare the perioperative outcomes, postoperative urinary control rates and positive surgical margin (PSM) rates of the robot-assisted laparoscopic radical prostatectomy combined anterior and posterior approach (AP-RARP) with the Retzius-sparing approach (RS-RARP) and anterior approach (anterior-RARP) in the treatment of prostate cancer. The main question it aims to answer was:

• The early therapeutic efficacy of the robot-assisted laparoscopic radical prostatectomy combined anterior and posterior approach

Participants has been underwent:

* AP-RARP
* RS-RARP
* anterior-RARP Researchers compared the three groups to see if AP-RARP combines the advantages of anterior and posterior RARP and is a feasible surgical option for the treatment of prostate cancer.

Detailed Description

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Conditions

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Prostatectomy Prostate Neoplasm

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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AP-RARP

the robot-assisted laparoscopic radical prostatectomy combined anterior and posterior approach

the robot-assisted laparoscopic radical prostatectomy

Intervention Type PROCEDURE

We collect medical data of 233 patients with clinically localized prostate cancer who underwent AP-RARP, RS-RARP or anterior-RARP. Perioperative outcomes, including operation time, intraoperative blood loss, intraoperative and postoperative transfusion, postoperative infection, and anastomotic leakage, were compared among the three groups. The postoperative continence rates and PSM rates were also compared.

RS-RARP

the robot-assisted laparoscopic radical prostatectomy with the Retzius-sparing approach

the robot-assisted laparoscopic radical prostatectomy

Intervention Type PROCEDURE

We collect medical data of 233 patients with clinically localized prostate cancer who underwent AP-RARP, RS-RARP or anterior-RARP. Perioperative outcomes, including operation time, intraoperative blood loss, intraoperative and postoperative transfusion, postoperative infection, and anastomotic leakage, were compared among the three groups. The postoperative continence rates and PSM rates were also compared.

anterior-RARP

he robot-assisted laparoscopic radical prostatectomy with anterior approach

the robot-assisted laparoscopic radical prostatectomy

Intervention Type PROCEDURE

We collect medical data of 233 patients with clinically localized prostate cancer who underwent AP-RARP, RS-RARP or anterior-RARP. Perioperative outcomes, including operation time, intraoperative blood loss, intraoperative and postoperative transfusion, postoperative infection, and anastomotic leakage, were compared among the three groups. The postoperative continence rates and PSM rates were also compared.

Interventions

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the robot-assisted laparoscopic radical prostatectomy

We collect medical data of 233 patients with clinically localized prostate cancer who underwent AP-RARP, RS-RARP or anterior-RARP. Perioperative outcomes, including operation time, intraoperative blood loss, intraoperative and postoperative transfusion, postoperative infection, and anastomotic leakage, were compared among the three groups. The postoperative continence rates and PSM rates were also compared.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* pathologically diagnosed with prostate cancer by prostate biopsy
* underwent robot-assisted laparoscopic surgery
* the surgery performed by Weidong Gan
* the extended pelvic lymphadenectomy (PLA) is performed on patients with high-risk prostate cancer (PSA≥20 ng/ml or Grade Group 4-5 or clinical stage ≥T2c) and those considered to have a possibility of lymph node metastasis based on imaging evaluation.

Exclusion Criteria

* Patients with a clinical and pathological TNM stage ≥T3b and N1
* patients with distant metastasis
* urinary incontinence before surgery
* received neoadjuvant therapy before surgery
Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Nanjing University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Fan Feng

Attending Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Urology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School

Nanjing, Jiangsu, China

Site Status

Countries

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China

Other Identifiers

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NanjingUSM202388

Identifier Type: -

Identifier Source: org_study_id