Evaluation of the HSV 1 & 2 Assay in Specimens From Symptomatic Subjects

NCT ID: NCT02270099

Last Updated: 2017-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

839 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-12-31

Study Completion Date

2017-06-30

Brief Summary

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This clinical performance study is being conducted to evaluate the performance of the Aptima Herpes Simplex Viruses 1 \& 2 assay for detection of herpes simplex virus (HSV) type 1 (HSV-1) and HSV type 2 (HSV-2) in swab samples prospectively collected from suspected HSV lesions. Specimens collected using swabs from viral transport medium (VTM)collection kits and Aptima swab collection kits will be evaluated.

Detailed Description

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Conditions

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Herpes Simplex Infections

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Subjects with suspected HSV Lesions

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* The subject has at least 1 active lesion (lesion with exudates and cellular material; eg, vesicle, ulcer) that is suspected to be caused by HSV (as determined by the clinician)
* The subject and/or legally authorized representative is willing and able to provide consent prior to study participation (a minor will need the documented consent of his/her parent or legal guardian, unless the site has an institutional review board-approved waiver for parental consent for minors)

Exclusion Criteria

* The subject has only HSV lesions without exudates and cellular material
* The subject used a topical or oral antiviral medication used to treat HSV within 21 days of enrollment
* Subject already participated in this study
* Subject has a history of illness that the principal investigator (PI) or designee considers could interfere with or affect the conduct, results, and/or completion of the study
* Subject has a history of illness that the PI or designee considers could create an unacceptable risk to the subject if enrolled in the study
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hologic, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Rainer Ziermann

Role: STUDY_DIRECTOR

Hologic, Inc.

Locations

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University of Alabama at Birmingham

Birmingham, Alabama, United States

Site Status

Elite Clinical Studies, LLC

Phoenix, Arizona, United States

Site Status

Sherif Khamis MD, Inc

Canoga Park, California, United States

Site Status

Mills Clinical Research

Los Angeles, California, United States

Site Status

Planned Parenthood of the Rocky Mountains

Denver, Colorado, United States

Site Status

Yale School of Medicine

New Haven, Connecticut, United States

Site Status

Perimeter Institute for Clinical Research, Inc. (PICR Clinic)

Atlanta, Georgia, United States

Site Status

Advanced Clinical Research

Boise, Idaho, United States

Site Status

Indiana University School of Medicine

Indianapolis, Indiana, United States

Site Status

LSU Health Science Center

New Orleans, Louisiana, United States

Site Status

LSU Health Science Center - Shreveport

Shreveport, Louisiana, United States

Site Status

IRC Clinics

Towson, Maryland, United States

Site Status

University of Mississippi Medical Center/Crossroads Clinic (MSDH)

Jackson, Mississippi, United States

Site Status

Quality Clinical Research Inc.

Omaha, Nebraska, United States

Site Status

Rochester Clinical Research, Inc.

Rochester, New York, United States

Site Status

Laboratory Corporation of America

Burlington, North Carolina, United States

Site Status

Westover Heights Clinic

Portland, Oregon, United States

Site Status

Planned Parenthood of Southeastern Pennsylvania

Philadelphia, Pennsylvania, United States

Site Status

Geneuity Clinical Research Services

Maryville, Tennessee, United States

Site Status

Planned Parenthood Gulf Coast, Inc.

Houston, Texas, United States

Site Status

Center for Clinical Studies

Webster, Texas, United States

Site Status

American Regional University Pathologists

Salt Lake City, Utah, United States

Site Status

Countries

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United States

Other Identifiers

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A10921-HSVPS-CSP-01

Identifier Type: -

Identifier Source: org_study_id

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