A Two Arm, Multi-Site Clinical Evaluation of the ARIES HSV 1&2 Assay in Symptomatic Patients

NCT ID: NCT02092233

Last Updated: 2015-07-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1963 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Brief Summary

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The ARIES HSV 1\&2 Assay is a PCR based test for the direct detection and typing of herpes simplex virus (HSV 1 \& 2) DNA.

The objective is to establish the diagnostic accuracy of ARIES HSV-1\&2 Assay.

Detailed Description

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The ARIES HSV 1\&2 Assay is a polymerase chain reaction (PCR) based qualitative in vitro diagnostic test for the direct detection and typing of herpes simplex virus (HSV 1 \& 2) DNA in male external and internal anogenital, female external and internal anogenital (vaginal), oral and skin lesion specimens.

The objective is to establish the diagnostic accuracy of ARIES HSV-1\&2 Assay through a multi-site, method comparison on prospectively collected, left-over de-identified, clinical specimens (i.e. all-comers accrued at enrolled clinical sites between pre-determined dates) as an aid in the diagnosis of herpes infection.

Conditions

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Herpes

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Blinded, Prospective Arm

The diagnostic accuracy for lesions from individuals suspected of having a herpes infection will be evaluated in prospectively collected, left-over de-identified, clinical specimens accrued between pre-defined dates.

No interventions assigned to this group

Blinded, Pre-selected Arm

For specimen types that are less common, banked, pre-selected, positive clinical specimens will be tested.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

The specimen is from one of the following lesion sources: male internal and external anogenital, female internal anogenital, female external anogenital, oral or skin The specimen is collected and maintained in unexpired Copan universal transport medium

Exclusion Criteria

The specimen was not properly collected, transported or stored according to instructions provided by Sponsor
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Luminex Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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David Himsworth

Role: STUDY_DIRECTOR

Luminex Corporation

Locations

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Baystate Medical Center

Springfield, Massachusetts, United States

Site Status

Tricore

Albuquerque, New Mexico, United States

Site Status

Labcorp

Burlington, North Carolina, United States

Site Status

Countries

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United States

Other Identifiers

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LMA-HSV-01-CS-001

Identifier Type: -

Identifier Source: org_study_id

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