Effect of FAS and FAS Ligand Polymorphisms on Patients With Platinum-Based -Treated Malignant Pleural Mesothelioma
NCT ID: NCT02269878
Last Updated: 2018-01-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
68 participants
OBSERVATIONAL
2014-04-30
2016-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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people with MPM with Thymine/Thymine,Thymine/cytosine genotype
according to Single nucleotide polymorphism analysis of rs 763110, people have one of the following genotypes, Thymine/Thymine,Thymine/Cytosine,Cytosine/Cytosine. we will assign Thymine/Thymine, Thymine/Cytosine to group one and Cytosine/Cytosine to group two. for rs 1800682 people will have one of the following genotypes Adenine/Adenine, Adenine/Guanine or Guanine/Guanine.
No interventions assigned to this group
people with MPM, Cytosine/Cytosine genotype
according to Single nucleotide polymorphism analysis of rs 763110, people have one of the following genotypes, Thymine/Thymine,Thymine/Cytosine,Cytosine/Cytosine. we will assign Thymine/Thymine, Thymine/Cytosine to group one and Cytosine/Cytosine to group two. for rs 1800682 people will have one of the following genotypes Adenine/Adenine, Adenine/Guanine or Guanine/Guanine.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Age of 18 years or more.
* first-line chemotherapy with platinum-Based agents
Exclusion Criteria
* pregnancy or lactation or any other reason preventing him from taking platinum-Based chemotherapy (AST more than 2.5\* Upper Limit of Normal or Serum bilirubin more than 1.5\* Upper Limit of Normal)
18 Years
ALL
No
Sponsors
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Ain Shams University
OTHER
Responsible Party
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Ahmed Mohammed Abdo Mohammed Salem
African Union organization St. Abbsia, Cairo, Egypt
Locations
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Ain Shams University Hospitals
Cairo, Abbasia, Egypt
Countries
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Other Identifiers
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Master (No14)
Identifier Type: -
Identifier Source: org_study_id
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