Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI (SERENADE)
NCT ID: NCT02246634
Last Updated: 2024-10-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
282 participants
INTERVENTIONAL
2014-08-31
2031-12-31
Brief Summary
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Findings of liver MRIs as reported by radiology PI will be shared with their local MDT who make decisions as appropriate, including the management of any identified liver metastases, according to local protocol.
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Diffusion Weighted MRI scan
Patients who are enrolled in the study will undergo an additional diffusion weighted MRI (T2W, DWI and ADC sequences) of the liver.
Diffusion Weighted MRI scan
Liver metastases found on the additional DW-MRI scans will be discussed at MDT and treated according to local site policy.
Interventions
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Diffusion Weighted MRI scan
Liver metastases found on the additional DW-MRI scans will be discussed at MDT and treated according to local site policy.
Eligibility Criteria
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Inclusion Criteria
2. Have a negative CT or includes no confirmatory evidence of liver metastases
3. Is able to undergo treatment if liver metastasis is found
4. Have provided written informed consent to participate in the study
5. Be aged 16 years or over
Exclusion Criteria
2. Have metastatic disease
3. Have a synchronous second malignancy
4. Are contraindicated for MRI
5. Has a T3b or below low rectal tumour without EMVI or N1c
16 Years
ALL
No
Sponsors
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Pelican Cancer Foundation
OTHER
Imperial College London
OTHER
Responsible Party
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Principal Investigators
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Gina Brown
Role: PRINCIPAL_INVESTIGATOR
Imperial College London
Locations
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Macclesfield District General Hospital
Macclesfield, Cheshire, United Kingdom
Queen's Hospital
Burton-on-Trent, Derbyshire, United Kingdom
Broomfield Hospital
Chelmsford, Essex, United Kingdom
Royal Bolton Hospital
Bolton, Greater Manchester, United Kingdom
Medway Maritime Hospital
Gillingham, Kent, United Kingdom
University Hospital of South Manchester & Manchester Royal Infirmary
Wythenshawe, Manchester, United Kingdom
Royal Liverpool Hospital
Liverpool, Merseyside, United Kingdom
Royal Stoke University Hospital
Stoke-on-Trent, Staffordshire, United Kingdom
Royal Marsden Hospital
Sutton, Surrey, United Kingdom
Royal Gwent Hospital
Newport, Wales, United Kingdom
George Eliot Hospital
Nuneaton, Warwickshire, United Kingdom
Salisbury District Hospital
Salisbury, Wiltshire, United Kingdom
Queen Alexandra Hospital
Portsmouth, , United Kingdom
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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DOCUMAS: 17HH4153
Identifier Type: -
Identifier Source: org_study_id
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