Effects of High Oleic Palm Olein, Virgin Olive Oil and Coconut Oil Diets on Markers Selected in Malaysian

NCT ID: NCT02245113

Last Updated: 2014-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-12-31

Study Completion Date

2014-07-31

Brief Summary

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This study will be comparing human body responses by the effects of diets cooked with NoveLin, virgin olive oil and RBD coconut oil.

Detailed Description

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NoveLin has high content of monounsaturate fatty acids - oleic acid (C18:1) which is the predominant fatty acid and in this study NoveLin is used as cooking fat in compare with olive oil. Olive oil is the world's most commonly eaten monounsaturated oil which contains 55 - 83% oleic acid. Consumption of olive oil gives numerous health benefits on lowering total and LDL cholesterol, reducing LDL cholesterol's, lowering blood clotting factors, and lowering blood pressure. Coconut oil is the richest source of medium chain fatty acid and it has greater than 90% of saturated fatty acid with dominant fatty acid of lauric acid (C12:0). RBD coconut oil is used as positive control in this study.

Conditions

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Overweight

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

SINGLE

Participants

Study Groups

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Test Fat P

Test fat, n= 10 (minimum), 6 weeks intervention, Intervention 1, Intervention 2, and Intervention 3.

Group Type EXPERIMENTAL

diets

Intervention Type OTHER

Feeding trial for 6 weeks (week 0 - baseline). The experimental diets are comprised of 30% kcal fat, 15% kcal protein and 55% kcal carbohydrate. Each of the test fat contributes to two-thirds of total dietary fat will be compared.

Test Fat Q

Test fat, n= 10 (minimum), 6 weeks intervention, Intervention 1, Intervention 2, and Intervention 3.

Group Type EXPERIMENTAL

diets

Intervention Type OTHER

Feeding trial for 6 weeks (week 0 - baseline). The experimental diets are comprised of 30% kcal fat, 15% kcal protein and 55% kcal carbohydrate. Each of the test fat contributes to two-thirds of total dietary fat will be compared.

Test Fat R

Test fat, n= 10 (minimum), 6 weeks intervention, Intervention 1, Intervention 2, and Intervention 3.

Group Type EXPERIMENTAL

diets

Intervention Type OTHER

Feeding trial for 6 weeks (week 0 - baseline). The experimental diets are comprised of 30% kcal fat, 15% kcal protein and 55% kcal carbohydrate. Each of the test fat contributes to two-thirds of total dietary fat will be compared.

Interventions

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diets

Feeding trial for 6 weeks (week 0 - baseline). The experimental diets are comprised of 30% kcal fat, 15% kcal protein and 55% kcal carbohydrate. Each of the test fat contributes to two-thirds of total dietary fat will be compared.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* males and females aged 20-60 years
* BMI 23 - 27.5 kg/m2
* free from any disease
* not on any medication or treatment associated with reduction of CVD
* non-smokers and non-heavy drinker or having smoking or alcoholic history
* not pregnant or lactating
* willing and able to comply

Exclusion Criteria

* people on weight reduction therapy/program
* people on cholesterol reduction medicatio
* have one or more of the chronic diseases
* people with blood clotting problem/ coagulopathy / deep vein thrombosis.
* hypertensive persons (systolic pressure \> 140 mmHg, diastolic pressure \> 90 mmHg)
* female who is pregnant
* people travel to overseas during feeding.
Minimum Eligible Age

20 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universiti Putra Malaysia

OTHER

Sponsor Role collaborator

IMU University, Malaysia

OTHER

Sponsor Role collaborator

Malaysia Palm Oil Board

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Voon Phooi Tee, PhD

Role: PRINCIPAL_INVESTIGATOR

MPOB

Lee Sin Tien, BSc

Role: PRINCIPAL_INVESTIGATOR

UPM

Norhaizan Md Esa, PhD

Role: PRINCIPAL_INVESTIGATOR

UPM

Tony Ng Kock Wai, PhD

Role: PRINCIPAL_INVESTIGATOR

IMU

Verna Lee Kar Mun, PhD

Role: PRINCIPAL_INVESTIGATOR

IMU

Locations

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MPOB

Kajang, Selangor, Malaysia

Site Status

Countries

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Malaysia

Other Identifiers

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R002302000

Identifier Type: -

Identifier Source: org_study_id

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