Postprandial Blood Cell Transcriptome of Normal Weight and Obese Subjects to 3 Caloric Doses of a High-fat Meal

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-03-31

Study Completion Date

2013-11-30

Brief Summary

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The study will quantitatively evaluate the metabolic response of normal weight and obese subjects to three high-fat meals differing in caloric dose by analysing the postprandial blood transcriptome.

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Detailed Description

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Conditions

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Obesity Nutritional Intervention

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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normal weight subjects

Group Type EXPERIMENTAL

high-fat meal A

Intervention Type OTHER

high-fat meal B

Intervention Type OTHER

high-fat meal C

Intervention Type OTHER

obese subjects

Group Type EXPERIMENTAL

high-fat meal A

Intervention Type OTHER

high-fat meal B

Intervention Type OTHER

high-fat meal C

Intervention Type OTHER

Interventions

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high-fat meal A

Intervention Type OTHER

high-fat meal B

Intervention Type OTHER

high-fat meal C

Intervention Type OTHER

Other Intervention Names

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high-fat meal consisting of 500 kcal high-fat meal B consisting of 1000 kcal high-fat meal C consisting of 1500 kcal

Eligibility Criteria

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Inclusion Criteria

* age 25-50
* 20\<BMI\>25
* waist circumference \<94cm

* age 25-50
* 30\<BMI\>40
* waist circumference \>102cm

Exclusion Criteria

* physiological or psychological diseases
* allergies to food or intolerance to high-fat meal
* vegetarians, vegans
* chronic intake of drugs
* smokers
* diabetes mellitus type I and II
* debiliating kidney disease
* debiliating liver disease
* clinically established coronary heart diseases
* ingestion of vitamins or dietary supplements during the course of the study

Minimum Eligible Age

25 Years

Maximum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes