Cytokines of Patients With Transversus Abdominis Plane Block After Laparoscopic Colonic Surgery

NCT ID: NCT02219542

Last Updated: 2015-07-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-08-31

Study Completion Date

2015-02-28

Brief Summary

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The investigators designed a study to determine whether with combined general-transversus abdominis plane block anesthesia or standard general anaesthetic would provide same level of cytokines in patients undergoing Laparoscopic Colonic Surgery.

Detailed Description

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The investigators designed a study to determine whether combined general-transversus abdominis plane block anesthesia or standard general anaesthetic would provide same level of cytokine in patients undergoing Laparoscopic Colonic Surgery.

Conditions

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Laparoscopic Colonic Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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a standard general anesthesia

a standard general anesthesia and with transversus abdominis plane block 20 ml 0.9% sodium chloride

Group Type PLACEBO_COMPARATOR

transversus abdominis plane block

Intervention Type DRUG

transversus abdominis plane block with 20 mL saline

transversus abdominis plane block

a standard general anesthesia with transversus abdominis plane block 20 mL 0.25% ropivacaine

Group Type EXPERIMENTAL

transversus abdominis plane block

Intervention Type DRUG

transversus abdominis plane block with 20 mL 0.25% ropivacaine

Interventions

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transversus abdominis plane block

transversus abdominis plane block with 20 mL saline

Intervention Type DRUG

transversus abdominis plane block

transversus abdominis plane block with 20 mL 0.25% ropivacaine

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* •Participants were deemed eligible if they were candidates for spinal anesthesia undergoing Laparoscopic Colonic Surgery

Exclusion Criteria

* •Existing cognitive impairment as evidenced by Mini-Mental State Examination scores below 24 (of the 30 possible points)

* A history of neurological and psychiatric diseases including stroke, and psychosis
* Severe visual or hearing impairment
* Unwillingness to comply with the protocol or procedures
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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China Medical University, China

OTHER

Sponsor Role lead

Responsible Party

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Wen-fei Tan

Associate proffessor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hong Ma, M.D.,PhD

Role: STUDY_CHAIR

The department of Anesthesiology

Locations

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the First Hospital of China Medical University

Shenyang, Liaoning, China

Site Status

Countries

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China

Other Identifiers

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20140804

Identifier Type: -

Identifier Source: org_study_id

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