iTotal Pilot Study of ConforMIS Custom Total Knee Implant

NCT ID: NCT02186587

Last Updated: 2023-05-23

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-06-30

Study Completion Date

2016-04-30

Brief Summary

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To compare the outcomes of patients receiving the ConforMIS custom total knee implant to the outcomes of patients who receiving an off-the-shelf total knee implant.

Hypothesis: Patient-specific, custom total knee implants manufactured from patient CT data, and implanted with CT-navigated custom instruments will show faster functional recovery, including gait and patient functional outcome scores, when compared to standard, off-the-shelf total knee components inserted with non-navigated instruments (the present standard of care in total knee surgery).

Detailed Description

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The experimental design was changed based on enrollment hurdles to be a single cohort observational study where ConforMIS patients were enrolled and followed for 6 months with 6 minute walk used as the primary outcome measure.

Conditions

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Knee Arthroplasty, Total

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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ConforMIS

Subjects who receive a ConforMIS custom total knee implant.

Group Type OTHER

ConforMIS custom total knee

Intervention Type DEVICE

Total knee arthroplasty using ConforMIS custom total knee system with follow-up at 6 months

Interventions

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ConforMIS custom total knee

Total knee arthroplasty using ConforMIS custom total knee system with follow-up at 6 months

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

\- undergoing total knee arthroplasty

Exclusion Criteria

\- BMI \>40
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Missouri-Columbia

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sonny Bal, MD

Role: PRINCIPAL_INVESTIGATOR

Professor - PI

Locations

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Missouri Orthopaedic Institute

Columbia, Missouri, United States

Site Status

Countries

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United States

Other Identifiers

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1206872

Identifier Type: -

Identifier Source: org_study_id

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