A Single Time-Point Study to Evaluate the ConforMIS iTotal® (CR) Knee Versus Off-the-Shelf

NCT ID: NCT02251522

Last Updated: 2023-10-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

873 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-10-31

Study Completion Date

2016-12-31

Brief Summary

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It has been noted that patients "dramatically overestimate their functional ability early after surgery." Despite use of assistive devices increasing and functional testing scores decreasing post-surgery, the patient reported outcome scores fail to show worsening. Outcome questionnaires will be administered and functional testing will be conducted on all patients to capture these changes.

Detailed Description

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The functional testing used in this study consists of tests that physical therapists use daily as objective methods to assess patients' functional status. The testing is designed to closely mimic daily activities that the patients are familiar with.

Conditions

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Osteoarthritis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

OTHER

Study Groups

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ConforMIS iTotal Knee Replacement System

Patients who have had an iTotal knee replacement at least 6 months prior to testing

ConforMIS Total Knee Replacement System

Intervention Type DEVICE

Total knee replacement system using a patient specific implant.

Off-the-Shelf Knee Replacement System

Patients who have had an off-the-shelf knee replacement at least 6 months prior to testing

Off-the-Shelf Knee Replacement System

Intervention Type DEVICE

Total knee replacement system not using a patient specific implant.

Interventions

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ConforMIS Total Knee Replacement System

Total knee replacement system using a patient specific implant.

Intervention Type DEVICE

Off-the-Shelf Knee Replacement System

Total knee replacement system not using a patient specific implant.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Implant must be at least 6 months post-op and doing well
* Patient has had a total CR knee implant
* \> 18 years of age

Exclusion Criteria

* Simultaneous bilateral procedure occurred
* BMI \> 40
* Other physical disability that requires an aid for walking or disability affecting the hips, spine, contralateral knee or other joint that limits function
* Participation in another clinical study which would confound results
* Inability to complete the protocol in the opinion of the clinical staff due to safety or other reasons
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Restor3D

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Robert Tait, MD

Role: PRINCIPAL_INVESTIGATOR

Orthopaedic Institute of Henderson

Mary O'Connor, MD

Role: STUDY_CHAIR

Yale University

Locations

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Denver-Vail Orthopedics

Parker, Colorado, United States

Site Status

Institute for Orthopaedic Surgery & Sports Medicine

Fort Myers, Florida, United States

Site Status

Baptist Health South Florida

Miami, Florida, United States

Site Status

Coastal Orthopaedic & Sports Medicine Ctr

Port Saint Lucie, Florida, United States

Site Status

Bethesda Orthopedic

Bethesda, Maryland, United States

Site Status

Excel Orthopaedic Specialists

Woburn, Massachusetts, United States

Site Status

Great Lakes Bone & Joint Center

Battle Creek, Michigan, United States

Site Status

Lederman-Kwartowitz Center for Orthopedics and Sports Medicine

West Bloomfield, Michigan, United States

Site Status

Orthopaedic Institute of Henderson

Henderson, Nevada, United States

Site Status

St. Lawrence Health System

Potsdam, New York, United States

Site Status

Orthopedic Specialties of Spartanburg

Spartanburg, South Carolina, United States

Site Status

Advanced Orthopedics & Sports Medicine

Cypress, Texas, United States

Site Status

Vitos Orthopädische Klinik Kassel

Kassel, , Germany

Site Status

MedArtes

Neutraubling, , Germany

Site Status

Elblandkliniken Stiftung

Radebeul, , Germany

Site Status

Sportklinik Stuttgart

Stuttgart, , Germany

Site Status

Countries

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United States Germany

Other Identifiers

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14-001

Identifier Type: -

Identifier Source: org_study_id

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