A Randomized, Open-label, Single Dose, Two-way Crossover Clinical Trial to Compare the Safety, Pharmacokinetic Profiles of UI15AML055MT and Amosartan® Tablet 5/50 mg After a Single Oral Administration in Healthy Male Volunteers

NCT ID: NCT02166398

Last Updated: 2015-06-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

46 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-06-30

Study Completion Date

2014-12-31

Brief Summary

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A randomized, open-label, single dose, two-way crossover clinical trial to compare the safety, pharmacokinetic profiles of UI15AML055MT and Amosartan® tablet 5/50 mg after a single oral administration in healthy male volunteers

Detailed Description

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A randomized, open-label, single dose, two-way crossover clinical trial to compare the safety, pharmacokinetic profiles of UI15AML055MT and Amosartan® tablet 5/50 mg after a single oral administration in healthy male volunteers

Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Amosartan 5/50 tab

Amosartan 5/50 tab given by oral administration

Group Type ACTIVE_COMPARATOR

Amosartan 5/50

Intervention Type DRUG

tab, PO

UI15AML055MT tab

UI15AML055MT tab given by oral administration

Group Type EXPERIMENTAL

UI15AML055MT

Intervention Type DRUG

tab, PO

Interventions

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UI15AML055MT

tab, PO

Intervention Type DRUG

Amosartan 5/50

tab, PO

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients over 20 under 45 years of age
* BMI state over 19 under 27

Exclusion Criteria

* mean sit SBP≥100mmHg or mean sit DBP≥150mmHg at screening
* mean sit SBP≥65mmHg or mean sit DBP≥95mmHg at screening
* Patients showed clinically significant hematological finding, patients with renal diseases (serum creatinine), patients with hepatic disease (ALT or AST)
* History of alcohol or drug abuse
* Positive to pregnancy test, nursing mother, has an intention on pregnancy
* Considered by investigator as not appropriate to participate in the clinical study with othe reason
Minimum Eligible Age

20 Years

Maximum Eligible Age

45 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Korea United Pharm. Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Seoul National University Hospital

Seoul, Jongno-gu, South Korea

Site Status

Countries

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South Korea

Other Identifiers

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KUP-UNSD-101

Identifier Type: -

Identifier Source: org_study_id

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