Predictors of Exposure Success in Public Speaking Anxiety

NCT ID: NCT02163148

Last Updated: 2015-05-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

24 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-05-31

Study Completion Date

2014-12-31

Brief Summary

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Anxiety disorders are common and impairing. Although exposure therapy is one of the most effective treatments for anxiety, some individuals do not fully respond to treatment, and these individual differences are not well understood. Exposure therapy involves repeated, deliberate, safe engagement with a feared stimulus without the feared outcome occurring. This treatment is thought to work through a type of emotional learning called fear extinction. This study aims to look at links between fear extinction learning and exposure success, with the overall goal of better understanding who is likely to respond best to exposure therapy and why.

Detailed Description

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Conditions

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Performance Anxiety

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Public Speaking Anxiety

Intervention to be administered: One speech exposure session.

Massed speech exposure session

Intervention Type BEHAVIORAL

One session consisting of 4 speech exposures, each 5 minutes long.

Interventions

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Massed speech exposure session

One session consisting of 4 speech exposures, each 5 minutes long.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Score of at least 20 on the PRCS
* Age 18-55
* English fluency

Exclusion Criteria

* Psychotropic medication use in the past 4 weeks
* Past experience with exposure based therapy
* History of bipolar disorder, psychotic disorder, or substance dependence
* Current major depressive disorder of greater than moderate severity (defined as a score on the 9 item Patient Health Questionnaire of greater than 14)
* Clinically significant suicidal or homicidal ideation
* Non-removable ferrous metal
* Current significant neurological conditions
* History of loss of consciousness greater than 5 minutes duration
* Pregnant
* Claustrophobic
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of California, San Diego

OTHER

Sponsor Role lead

Responsible Party

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Tali Manber Ball

Doctoral Candidate

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Tali M Ball, MA

Role: PRINCIPAL_INVESTIGATOR

UCSD

Locations

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UCSD Psychiatry Research

San Diego, California, United States

Site Status

Countries

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United States

References

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Ball TM, Knapp SE, Paulus MP, Stein MB. Brain activation during fear extinction predicts exposure success. Depress Anxiety. 2017 Mar;34(3):257-266. doi: 10.1002/da.22583. Epub 2016 Dec 6.

Reference Type DERIVED
PMID: 27921340 (View on PubMed)

Other Identifiers

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UCSDIRB-130313

Identifier Type: -

Identifier Source: org_study_id

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